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Nucleic Acids and Molecular Biology pp 217–225Cite as

Nucleosome Positioning

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Part of the book series: Nucleic Acids and Molecular Biology ((NUCLEIC,volume 7))

Abstract

Nucleosome positioning is one of the most discussed and least well understood aspects of histone-DNA organization in chromatin. At issue is the location of nucleosomes along the DNA sequence, which may be important for transcription, replication, and other DNA transactions. Nucleosomes have been shown to occlude promoters and origins of replication, and to interfere with specific protein-binding to some regulatory sequences as well. The question arises of how these inhibitory effects are overcome.

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Author information

Authors and Affiliations

  1. Department of Cell Biology, Stanford University School of Medicine, Stanford, California, 94305, USA

    Y. Lorch

Authors
  1. R. D. Kornberg
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  2. Y. Lorch
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Editor information

Editors and Affiliations

  1. Max-Planck-Institut für Experimentelle Medizin, Hermann-Rein-Straße 3, 37075, Göttingen, Germany

    Fritz Eckstein

  2. Biochemistry Department, University of Dundee, DD1 4HN, Dundee, UK

    David M. J. Lilley

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© 1993 Springer-Verlag Berlin Heidelberg

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Kornberg, R.D., Lorch, Y. (1993). Nucleosome Positioning. In: Eckstein, F., Lilley, D.M.J. (eds) Nucleic Acids and Molecular Biology. Nucleic Acids and Molecular Biology, vol 7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77950-3_13

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  • DOI: https://doi.org/10.1007/978-3-642-77950-3_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77952-7

  • Online ISBN: 978-3-642-77950-3

  • eBook Packages: Springer Book Archive

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