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Pathogenetische Bedeutung der intestinalen Bakterienflora für die Entwicklung chronischer intrahepatischer Cholangitiden

  • Conference paper
Ökosystem Darm IV

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Zusammenfassung

Enterale Mikroorganismen oder deren Komponenten können durch Aszension in den Gallenwegen, auf lymphogenem Wege oder auf dem Blutwege über die Pfortader bzw. systemische Zirkulation zur Leber gelangen und in unterschiedlicher Weise mit der Leber interagieren. Die intrahepatischen Folgen richten sich nach den biologischen Aktivitäten und der Konzentration der Erreger bzw. der Erregerkomponenten. So wird man hinsichtlich der hepatologischen Bedeutung enteraler Mikroorganismen vor allem 3 Aspekte berücksichtigen müssen: die Leber als Zielorgan von Infektionserregern, die Leber als Clearanceorgan mit metabolischen und detoxifizierenden Funktionen und schließlich die Leber als immunologisches Organ mit der Synthese abwehraktiver Mediatoren.

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Authors
  1. U. Hopf
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  2. R. Stemerowicz
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  3. V. König
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  4. S. Küther
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  5. H. Lobeck
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  6. K. Miksits
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  7. J. Wagner
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Editor information

Editors and Affiliations

  1. Hygienisches Institut, Marckmannstraße 129a, 2000, Hamburg 26, Deutschland

    Jochen Bockemühl (Direktor der Medizinaluntersuchungsanstalt und Leiter der Abt. für Enterobacteriaceae) (Direktor der Medizinaluntersuchungsanstalt und Leiter der Abt. für Enterobacteriaceae)

  2. Städtisches Krankenhaus Neuperlach, Oskar-Maria-Graf-Ring 51, D-8000, München 83, Deutschland

    R. Ottenjann (ehem. Chefarzt der I. Medizinischen Abteilung) (ehem. Chefarzt der I. Medizinischen Abteilung)

  3. Abt. für Innere Medizin, Schwerpunkt Gastroenterologie, Med. Klinik und Poliklinik, Klinikum Steglitz der Freien Univ. Berlin, Hindenburgdamm 30, 1000, Berlin 45, Deutschland

    Martin Zeitz

  4. Gastroenterologie u. Allgemein. Innere Medizin, Städtisches Krankenhaus Solingen, 5650, Solingen 1, Deutschland

    Gerd Lux (Chefarzt der Med. Klinik) (Chefarzt der Med. Klinik)

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© 1993 Springer-Verlag Berlin Heidelberg

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Hopf, U. et al. (1993). Pathogenetische Bedeutung der intestinalen Bakterienflora für die Entwicklung chronischer intrahepatischer Cholangitiden. In: Bockemühl, J., Ottenjann, R., Zeitz, M., Lux, G. (eds) Ökosystem Darm IV. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77930-5_24

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  • DOI: https://doi.org/10.1007/978-3-642-77930-5_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-56198-9

  • Online ISBN: 978-3-642-77930-5

  • eBook Packages: Springer Book Archive

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