Abstract
Wound occlusion leads to an accleration of the healing time in chronic wounds. Winter [16] already showed that occlusive dressings speed epithelialization of superficial wounds. Modern wound healing technology takes advantage of this. Faster removal of necrotic tissue, formation of healthy granulation tissue and quick epithelialization are the effects of occlusive dressings. The accumulated wound fluid contains elements for a provisional matrix out of fibronectin and vitronectin which is used by migrating keratinocytes as a track during tissue remodeling [12]. Furthermore the accumulated wound fluid causes a stimulation of the cell populations. Positive effects of wound fluid on the proliferation of fibroblasts and endothelial have been shown [10]. The study presented here examined the effect of wound fluid on attachment and proliferation of cultured human keratinocytes.
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© 1995 Springer-Verlag Berlin Heidelberg
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Soehnchen, R.M., Hilbert, E., Zouboulis, C.C., Orfanos, C.E. (1995). Effect of Wound Fluid on Cultured Keratinocytes. In: Altmeyer, P., Hoffmann, K., el Gammal, S., Hutchinson, J. (eds) Wound Healing and Skin Physiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77882-7_32
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DOI: https://doi.org/10.1007/978-3-642-77882-7_32
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