Abstract
Optimal, uncomplicated wound healing requires a clean wound bed, free of damaged tissue and germs. Extensive and complete debridement of necrotic and infected areas, however, is not always achievable. In particular this applies to radiation damage to tissue and irradiation ulcers that are located in tissues covering internal organs, large vessels, nerve bundles and structures of functional importance, because of the risk of life threatening complications or severe functional impediment [1, 2]. In these cases one has to cope with the situation of being forced to cover nonradically excised tissue defects.
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References
Gilles HD, McIndoe AH (1935) The role of plastic surgery in burns due to Roentgen rays and radium. Ann Surg 101:979.
Marino H (1967) Biologic excision: its value in the treatement of radionecrotic lesions. Plast Reconstr Surg 40:180.
Fisher J, Wood MB, Shaw WW (1987) Experimental comparison of bone revascularisation by musculocutaneous and cutaneous flaps. Plast Reconstr Surg 79:81.
Khouri RK, Upton J, Shaw WW (1991) Prefabrication of composite free flaps through staged microvascular transfer: an experimental study. Plast Reconstr Surg 87:108.
Gosalin A, Chang N, Mathes S et al. (1990) A study of the relationship between blood flow and bacterial inoculation in musculocutaneous and fasciocutaneous flaps. Plast Reconstr Surg 86:1152.
Goldsmith HS, Griffith AL, Kupferman A et al. (1984) Lipid angiogenic factor from omentum. JAMA 252:2034.
Williams R (1990) Angiogenesis and greater omentum. In: Goldsmith HS (ed) The omentum. Research and clinical application. Springer, Berlin Heidelberg New York.
Huber B, Juhn A, Mohler D et al. (1990) Time and dose-dependent profile of omental angiogenic lipid factor on bone repair. In: Goldsmith HS (ed) The omentum. Research and clinical application. Springer, Berlin Heidelberg, New York.
Liebermann A, White H (1983) Defense mechanisms. In: Liebermann-Meffert D, White H (eds) The greater omentum. Anatomy, physiology, pathology, surgery. With an historical survey. Springer, Berlin Heidelberg New York.
Cassidy P (1900) Report of a severe X-ray injury. Med Rec 57:180.
Huntington TW (1901) Note on X-ray burns and their treatment. Ann Surg 34:808.
Davis JS (1920) The radical treatment of X-ray burns. Ann Surg 72:224.
Robinson DW (1975) Surgical problems in the excision and repair of irradiated tissues. Plast Reconstr Surg 55:41.
Holmstrom H, Johanson B (1972) Local radiation injury and its surgical treatment. Report of 170 cases. Scand J Plast Surg 6:156.
Gorgun B, Ermis MI (1989) Plastic surgery treatment of radiation induced injuries and tumors. Eur J Plast Surg 12:198.
Miller SH, Rudolph R (1990) Healing in the irradiated wound. Clin Plast Surg 17:503.
Mathes SJ, Feng LJ, Hunt TK (1983) Coverage of the infected wound. Ann Surg 198:420.
Russell RC, Graham DR, Feller AM et al. (1988) Experimental evaluation of the antibiotic carrying capacity of a muscle flap into a fibrotic cavity. Plast Reconstr Surg 81:162.
Eshima I, Mathes SJ, Paty P (1990) Comparison of the intracellular bacterial killing activity of leucocytes in musculocutaneous and random pattern flaps. Plast Reconstr Surg 86:541.
Calderon W, Change N, Mathes SJ (1986) Comparison of the effect of bacterial inoculation in mucsculocutaneous and fasciocutaneous flaps. Plast Reconstr Surg 77:785.
Milanov NO, Shilov BL (1989) Hemodynamic peculiarities of the greater omentum. Microsurgical autotransplantation. J Reconstr Microsurg 5:387.
Liebermann-Meffert D, Rist M (1989) Was leistet die Omentumplombe in der kolorektalen Tumorchirurgie? Eine 10-Jahreskontrolle. Schweiz Med Wochenschr 119:739.
Guber S, Rudolph R (1978) The myofibroblast. Surg Obstet Gynecol 146:641.
Beelen RH (1991) The greater omentum: physiology and immunological concepts. Neth J Surg 43:145.
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© 1995 Springer-Verlag Berlin Heidelberg
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Shilov, B., Milanov, N.O., Liebermann-Meffert, D. (1995). Biologic Activity of Tissue Flaps in the Treatment of Complicated Wounds. In: Altmeyer, P., Hoffmann, K., el Gammal, S., Hutchinson, J. (eds) Wound Healing and Skin Physiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77882-7_24
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DOI: https://doi.org/10.1007/978-3-642-77882-7_24
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