Zusammenfassung
Die Aktivierung des „intrinsic“-Gerinnungssystems wird durch Kontakt des Plasmas mit negativ geladenen Oberflächen eingeleitet. Als derartige Oberflächen wirken in vivo suBendotheliale Strukturen wie das Kollagen, die Basalmembranen und andere verschiedene Gewebsstrukturen. In vitro besitzen Glas, Kaolin, Celite und Ellagsäure vergleichbare Eigenschaften [1,7].
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
Literatur
Fuhrer G, Gallimore MJ, Heller W, Hofmeister H-E (1990) F XII. Review article. Blut 61:258
Goodnough LT, Saito H, Ratnoff GD (1983) Thrombosis or myocardial infarction in congenital clotting factor abnormalities and chronic thrombocytopenias: Areport of 21 patients and a review of 50 previously reported cases. Medicine 62:248
Hellstern P, Köhler M, Schmengler K, Doenecke P, Wenzel E (1983) Arterial and Venous Thrombosis and Normal Response to Streptokinase Treatment in a Young Patient with Severe Hageman Factor Deficiency. Acta Haematologica 69:123
Lämmle B, Wuillemin WA, Huber I, Krauskopf M, Zürcher C, Pflugshaupt R, Furlan M (1991) Thromboembolism and Bleeding Tendency in Congenital Factor XII Deficiency A Study on 74 Subjects from 14 Swiss Families. Thrombos Haemostas 65:117
Mannhalter C, Fischer M, Hopmeier P, Deutsch E (1987) Factor XII activity and antigen concentrations in patients suffering from recurrent thrombosis. Fibrinolysis 1:259
Ratnoff GD, Calopy JE (1955) A familial hemorrhagic trait associated with a deficiency of a clot-promoting fraction from plasma. J Clin Invest 34:602
Ratnoff GD, Rosenbaum JM (1958) Role of Hageman factor in the initiation of clotting by glass. Amer J Med 25:160
Revak SD, Cochrane CG, Johnson AR, Hugli TH (1974) Structural changes accompanying enzymatic activation of human Hageman factor. J Clin Invest 54:619
Saito H, Ratnoff GD, Pensky J (1976) Radioimmune assay of human Hageman factor (factor XII). J Lab Clin Med 88:506
Weiss HJ, Turitto VT, Vicic WJ, BaumgartnerHR (1984) Fibrin Formation, Fibrinopeptide A Release, and Platelet Thrombus Dimensions on Subendothelium Exposed to Flowing Native Blood: Greater in Factor XII and XI Than in Factor VIII and IX Deficiency. Blood 63:1004
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Zimmermann, R., Tecl, R., Korten, V. (1992). Rezidivierende thromboembolische Erscheinungen bei einer Patientin mit kongenitalem Faktor XII-Mangel. In: Landbeck, G., Scharrer, I., Schramm, W. (eds) 22. Hämophilie-Symposion Hamburg 1991. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77881-0_29
Download citation
DOI: https://doi.org/10.1007/978-3-642-77881-0_29
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-56096-8
Online ISBN: 978-3-642-77881-0
eBook Packages: Springer Book Archive