Skip to main content

Der Einfluß der Genetik auf die Geburtsmedizin

  • Conference paper
Gynäkologie und Geburtshilfe 1992
  • 7 Accesses

Zusammenfassung

Der Fortschritt der Genetik während der letzten Jahre hat sich auf die Schwangerschafts- und Geburtsmedizin wie auf keinem anderem Bereich der Humanmedizin bereits jetzt ausgewirkt, und für die Zukunft sind deutlich absehbar noch stärkere Einflüsse zu erwarten.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Holzgreve, W.: Sonographie Screening for anatomic defects. Semin. Perinatol. 14, 504–513, 1990

    PubMed  CAS  Google Scholar 

  2. Holzgreve, W., Miny, P, Gerlach, B., Westendorp, A., Ahleit, D., Horst, J.: Benefits of placental biopsies for rapid karyotyping in the second and third trimesters (late chorionic villus sampling) in high-risk pregnancies. Am. J.Obstet. Gynecol. 162, 1188–1192, 1990

    PubMed  CAS  Google Scholar 

  3. Wald, N.J., Cuckle, H.S., Densem, J.W., Nanchahal, K., Royston, P, Chard, T., Haddow, J.E., Knight, G.J., Palomaki, G.E., Canick, J.A.: Maternal serum Screening for Down’s Syndrome in early pregnancy. Brit. Med. J. 297, 883–887, 1988.

    Article  PubMed  CAS  Google Scholar 

  4. Holzgreve, W., Schloo, R., Tercanli, S., Miny, P, Schlegel, W.: Erfahrungen mit dem sogenannten „Triple-Screening“ des Down-Syndroms und Schlußfolgerungen für die Praxis. Schindler, A.E. (ed.): Biochemische Überwachung der Schwangerschaft, Stuttgart, Enke, 33–39, 1992

    Google Scholar 

  5. Holzgreve, W., Garritsen, H.S.P., Gänshirt-Ahlert, D.: Fetal cells in the maternal circulation. J. Repr. Med. 37, 1992

    Google Scholar 

  6. Bianchi, D.W., Flint, A.F., Pizzimenti, M.F., Knoll, J.H.M., Latt, S.A.: Isolation of fetal DNA from nucleated erythrocytes in maternal blood. Proc. Natl. Acad. Sci. 87, 3279–3283,1990

    Article  PubMed  CAS  Google Scholar 

  7. Tabor, A., Madse, M., Obel, E.B., Philip, J., Bang, J., Norgard-Pedersen, B.: Randomized controlled trial of genetic amniocentesis 4,606 risk women. Lancet 1,1287–1293,1986.

    Article  PubMed  CAS  Google Scholar 

  8. Benn, P.A., Hsu, L.Y.F.: Maternal cell contamination of amniotic fluid cell cultures: result of U.S. nationwide survey. Am Med. Genet. 15, 2927–305,1983

    Google Scholar 

  9. Gosden, C., Nicolaides, K.H., Rodeck, C.H.: Fetal blood sampling in investigation of chromosome mosaicism in amniotic fluid cell culture. Lancet 1, 613–616, 1988.

    Article  PubMed  CAS  Google Scholar 

  10. Hook, E.B., Willey, A.M.: Abortion because of unavailability of prenatal diagnosis. Lancet 2, 936, 1981.

    PubMed  CAS  Google Scholar 

  11. Blumberg, B.D., Golbus, M.S., Hanson, K.H.: The psychological sequelae of abortion perfomed for a genetic indication. Am. J. Obstet. Gynecol. 122, 799–808,1975.

    PubMed  CAS  Google Scholar 

  12. Muth, C., Exler, U., Miny, P., Holzgreve, W.: Die psychologische Verarbeitung eines Schwangerschaftsabbruches aus genetischer Indikation im zweiten Trimenon. Zeitschr. Geburtsh. Perinatol, 193, 96–99. 1989

    CAS  Google Scholar 

  13. Byrne, D.L., Marks, K., Braude, P.R., Nicolaides, K.H.: Amnifiltration in the first trimester: feasibility, technical aspects and cytological outcome. Ultrasound Obstet. Gynecol. 1, 320–324,1991.

    Article  PubMed  CAS  Google Scholar 

  14. Rooney, D.E., MacLachlan, N., Smith, J., Rebello, M.T., Loeffler, F.E., Beard, R.W., Rodeck, C.H., Coleman, D.V.: Early amniocentesis: a cytological evolution. Br. Med. J. 299, 25, 1989.

    Article  CAS  Google Scholar 

  15. Stripparo, L., Buscaglia, M., Longatti, L., Ghisoni, L., Dambrosio, F., Guerneri, S., Rosella, F., Lituania, M., Cordone, M., De Biasio, P., Passamonti, U., Gimelli, G., Cuoco, M.: Genetic amniocentesis: 505 cases performed before the 16th week of gestation. Prenat. Diagn. 10, 359–364, 1990.

    Article  PubMed  CAS  Google Scholar 

  16. Sundberg, K., Smidt-Jensen, S., Philip, J.: Amniocentesis with increased cell yield, obtained by filtration and reinjection of the amniotic fluid. Ultrasound Obstet. Gynecol. 1, 91–94, 1991.

    Article  PubMed  CAS  Google Scholar 

  17. Rebello, M.T., Gray, C.T.H., Rooney, D.E., Smith, J.H., Hackett, G.A., Loeffler, F.E., Horwell, D.H., Beard, R.W., Coleman, D.V.: Cytogenetic studies of amniotic fluid taken before the 15th week of pregnancy for earlier prenatal diagnosis: a report of 114 consecutive cases. Prenat. Diagn. 11, 35–40, 1991.

    Article  PubMed  CAS  Google Scholar 

  18. Elejalde, B.R. de Elejalde, M.M., Acuna, J.M., Thelen, D., Trujillo, C., Karrmann, M.: Prospective study of amniocentesis performed between weeks 9 and 16 of gestation: its feasibility, risks, complications and use in early genetic diagnosis. Am. J. Med. Genet. 35, 188.196,1990.

    Google Scholar 

  19. Byrne, D., Marks, K., Azar, G., Nicolaides, K.H.: Randomized study of early amniocentesis versus chorionic villus sampling: a technical and cytogenetic comparison of 650 patients. Ultrasound Obstet. Gynecol. 1, 235–240,1991.

    Article  PubMed  CAS  Google Scholar 

  20. Editorial: Chorion villus sampling: valuable addition or dangeruos alternative? Lancet 1, 1513–1515, 1991.

    Google Scholar 

  21. Ward, R.H.T., Modell, B., Petrou, M., Karagözlu, F., Doutratsos, E.: Method of sampling chorionic villi in the first trimester of pregnancy under guidance of real time ultrasound. Br. Med. J. 286, 1542, 1983.

    Article  CAS  Google Scholar 

  22. Holzgreve, W., Miny, P.: Chorionic villi samplimg with an echogenic catheter: experiences with the first 500 cases. J. Perinat. Med. 15, 244, 1987.

    Article  PubMed  CAS  Google Scholar 

  23. Smidt-Jensen, S., Hahnemann, N.: Transabdominal fine needle biopse from chorionic villi in the first trimester. Prenat. Diagn. 4, 163, 1984.

    Article  PubMed  CAS  Google Scholar 

  24. Brambati, B., Terzian, E., Tognoni, G.: Randomized clinical trial of transabdominal versus transcervical chorionic villus sampling methods. Prenat. Diagn. 11, 285–293, 1991.

    Article  PubMed  CAS  Google Scholar 

  25. Jackson, L.G., Zachary, J.M., Fowler, S.E., Desnick, R.J., Golbus, M.S., Leedbetter, D.H., Mahoney, M.J., Pergament, E., Simpson, J.L., Black, S.: A randomized comparison of transcervical and transabdominal chorionic villus sampling. N. Engl. J. Med. 327, 594–598, 1992.

    Article  PubMed  CAS  Google Scholar 

  26. Smidt-Jensen, S., Permin, M., Philip, J.: Samplimg success and risk by transabdominal chorionic villus sampling, transcervical chorionic villus sampling and amniocentesis: a randomized study. Ultrasound Obstet. Gynecol. 1, 86–90, 1991.

    Article  PubMed  CAS  Google Scholar 

  27. Young, S.R., Shipley, C.F., Wade, R.V., Edwards, J.G., Waters, M.B., Cantu, M.L., Best, R.G., Dennis, E.J.: Single center comparison of results of 1000 prenatal diagnoses with chorionic villus sampling and 1000 diagnoses with amniocentesis. Am. J. Obstet. Gynecol. 165, 255–263, 1991.

    PubMed  CAS  Google Scholar 

  28. Canadian Collaborative CVS-Amniocentasis Clinical Trial Group: Multicentre randomized clinical trial of chorionic villus sampling and amniocentesis. Lancet 1, 1–6, 1989.

    Google Scholar 

  29. MRC Working Party on the Evaluation of Chorionic Villus Sampling: Medical Research Council European Trial of Chorion villus sampling. Lancet 1, 1491–1499, 1991.

    Google Scholar 

  30. Rhoads, G.G., Jackson, L.G., Schlesselman, S.I., De la Cruz, F.F., Desnick, R.F., Golbus, M.S., Ledbetter, D.H., Lubs, H.A., Mahonney, M.J., Pergament, E., Simpson, J.L., Carpenter, R.J., Elias, S., Ginsberg, N.A., Goldberg, J.D., Hobbins, J.C., Lynch, L., Shiono, P.H., Wapner, R.J., Zachary, J.M.: The safety and efficacy of chorionic villus sampling for early prenatal diagnosis of cytogenetic abnormalities. N. Engl. J. Med. 320, 609, 1989.

    Article  PubMed  CAS  Google Scholar 

  31. Firth, H.V., Boyd, P.A., Chamberlain, P.Lp., MacKenzie, I.Z., Lindenbaum, R.H., Huson, S.M.: Severe limb abnormalities after chorion villus sampling at 56.66 days’ gestation. Lancet 1, 762–763, 1991.

    Article  Google Scholar 

  32. Burton, B.K., Schulz, C.J., Burd, L.I.: Limb anomalities associated with chorionic villus sampling. Obstet. Gynecol. 79, 726–730, 1992.

    PubMed  CAS  Google Scholar 

  33. Schloo, R., Miny, P, Holzgreve, W., Horst, J., Lenz, W.: Limb reduction defects following chorionic villus sampling. Am.J. Genet. in press.

    Google Scholar 

  34. Miny, P, Hammer, P, Gerlach, B., Tercanli, S., Horst, J., Holzgreve, W., Eiben, B.: Mosaicism and accuracy of prenatal cytogenetic diagnoses after chorionic villus sampling and placental biopsies. Prenat. Diagn. 11, 581–589, 1991.

    Article  PubMed  CAS  Google Scholar 

  35. Holzgreve, W., Golbus, M.S.: Prenatal diagnosis of Ornithine transcarbamylase deficiency utilizing fetal liver biopsy. Am. J.Hum. Genet. 36, 320–328, 1984.

    PubMed  CAS  Google Scholar 

  36. Watson, J.D.: The human genome project: Past, present and future. Science 218,44–49,1991.

    Google Scholar 

  37. National Research Council. Mapping and Sequencing the human genome. Washington, DC, National Academy Press, 1992.

    Google Scholar 

  38. Mealy, B.: Testimony on the possible uses and misuses of genetic information. Human Gene Therapy 3, 51–56 1992.

    Article  Google Scholar 

  39. Holtzmann, N.A. (ed.): Proceed with caution: predicting genetic risks in the recombinant DNA era. Baltimore and London, The John Hopkins University Press, 1989.

    Google Scholar 

  40. Handyside, A.H., Lesko, J.G., Tarin, J.J., Winston, R.M.L., Huges, M.R.: Birth of a normal girl after in vitro fertilization and preimplantition diagnostic testing for cystic fibrosis. N. Eng. J. Med. 327, 905–909, 1992.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Holzgreve, W., Miny, P. (1993). Der Einfluß der Genetik auf die Geburtsmedizin. In: Krebs, D., Berg, D. (eds) Gynäkologie und Geburtshilfe 1992. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77857-5_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-77857-5_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77858-2

  • Online ISBN: 978-3-642-77857-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics