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Klinische Wertigkeit von In-vitro-Sensitivitätstests

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Book cover Immuntherapie in der Uroonkologie

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Zusammenfassung

Salmon et al. (1978) haben wesentlich die Entwicklung von In-vitro-Sensitivitätstestverfahren (Soft-Agar-Stammzellverfahren, Human-Tumor-Cloning-Assay (HTCA)) beeinflußt. Daraus resultierte die Vorstellung, ein prädiktives Testsystem (sog. Onkobiogramm) zu etablieren, um vor Einleitung einer Chemotherapie bei metastasierten Malignomen die Therapieaussichten abzuschätzen (Von Hoff 1987). Für das Soft-Agar-Stammzell-Verfahren liegt die größte Erfahrung vor in der Korrelation von In-vitro-Sensitivitätstests und dem Responseverhalten der dazu korrespondierenden Patienten unter Therapie.

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Authors
  1. W. de Riese
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  2. E. Allhoff
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  3. A.-R. Hanauske
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  4. G. Lenis
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  5. S. Liedke
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  6. J. Atzpodien
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  7. H. Kirchner
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Editor information

Editors and Affiliations

  1. Urologische Klinik und Poliklinik, Universitätsklinikum Essen, Hufelandstr. 55, W-4300, Essen 1, Deutschland

    Herbert Rübben  & Mark Goepel  & 

  2. Urologische Universitätsklinik, Moorenstr. 5, W-4000, Düsseldorf 1, Deutschland

    Bernd J. Schmitz-Dräger

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© 1993 Springer-Verlag Berlin Heidelberg

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de Riese, W. et al. (1993). Klinische Wertigkeit von In-vitro-Sensitivitätstests. In: Rübben, H., Goepel, M., Schmitz-Dräger, B.J. (eds) Immuntherapie in der Uroonkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77830-8_4

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  • DOI: https://doi.org/10.1007/978-3-642-77830-8_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77831-5

  • Online ISBN: 978-3-642-77830-8

  • eBook Packages: Springer Book Archive

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