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Peptidergic Regulation of Smooth Muscle Contractility

  • Chapter
Gastrointestinal Regulatory Peptides

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 106))

Abstract

The main functions of the smooth muscle of the gut are to mix and propel intraluminal contents in a coordinated manner in order to facilitate the digestion and absorption of nutrients and expulsion of unabsorbed residue. These functions are determined by intrinsic electrical and mechanical properties of the muscle and their regulation by hormones and neurotransmitters. The myenteric plexus, one of the two main components of the enteric nervous system, is particularly important in the regulation of smooth muscle activity. This chapter will discuss peptide hormones and transmitters that are important in the regulation of smooth muscle activity in the gut.

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  1. J. R. Grider
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Editors and Affiliations

  1. Department of Veterinary Biology, Pharmacology Section, University of Minnesota, 1988 Fitch Avenue, Saint Paul, MN, 55108, USA

    David R. Brown Ph.D.

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Grider, J.R. (1993). Peptidergic Regulation of Smooth Muscle Contractility. In: Brown, D.R. (eds) Gastrointestinal Regulatory Peptides. Handbook of Experimental Pharmacology, vol 106. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77814-8_9

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  • DOI: https://doi.org/10.1007/978-3-642-77814-8_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77816-2

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