The Pressure-Volume Index (PVI) with Epidural Mass Expansion

  • E. K. Walsh
  • A. Schettini
Conference paper

Abstract

The pressure-volume index (PVI) is intended to provide a measure of the intracranial buffering capacity to be used in predicting the change in ICP course when the craniospinal system is subject to further volume increments. When an intraventricular bolus injection of volume AV is added, rapidly, to the intracranial system, it results in an increase in pressure from a baseline value, Po, to a pressure Pp > Po. It has been shown that the pressure-volume response of the system is nonlinear and can be characterized by a mono-exponential function [2]. In particular, P = Po exp(kΔV), where k = In10/PVI. It follows then that, for a single bolus injection, the value of the PVI is determined as PVI = ΔV/log(Pp/Po).

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References

  1. 1.
    Avezaat CJJ, van Eijndhoven JHM (1986) How does the craniospinal system cope with a disturbance of its volume? In: Miller JD, Teasdale GM, Rowan JO, Galbraith SL, Mendelow AD (eds) Intracranial Pressure VI. Springer, Berlin Heidelberg New York TokyoGoogle Scholar
  2. 2.
    Marmarou A, Shulman K, La Morgese J (1975) Compartmental analysis of compliance and outflow resistance of the cerebrospinal fluid system. J Neurosurg 43:523–534PubMedCrossRefGoogle Scholar
  3. 3.
    Miller JD, Leech PJ, Pickard JD (1975) Volume-pressure response in various experimental and clinical conditions. In: Lundberg N, Ponten U, Brock M (eds) Intracranial Pressure II. Springer, Berlin Heidelberg New York TokyoGoogle Scholar
  4. 4.
    Schettini A, Walsh EK (1988) Brain tissue elastic behavior and experimental brain compression. Am J Physiol 255:R799–R805PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • E. K. Walsh
    • 1
    • 2
  • A. Schettini
    • 1
    • 2
  1. 1.College of EngineeringUniversity of FloridaGainesvilleUSA
  2. 2.Research ServiceMcGuire Veterans Administration Medical CenterRichmondUSA

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