Cerebral Perfusion Pressure Management of Head Injury

  • M. J. Rosner
  • S. D. Rosner


Previous work has demonstrated a causal relationship between unstable cerebral perfusion pressure (CPP) and the development of intracranial pressure (ICP) waves [3]. The genesis of this CPP instability has usually (though not exclusively) been decrements in systemic arterial blood pressure (SABP). A simple model termed the “Vasodilatory Cascade” has been developed which demonstrates the interrelationships which lead to the complex interaction of SABP, ICP, and CPP [5]. More importantly, the “Cascade” model in a more complex form leads directly to a model which helps interrelate both positive and negative aspects of many therapeutic modalities and their effect upon the whole system. From this understanding, a model upon which therapy [6] can be based has been developed and serves as the basis for the current report.


Traumatic Brain Injury Emergency Medical Service Intracranial Hypertension Cerebral Perfusion Pressure Severe Head Injury 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • M. J. Rosner
    • 1
  • S. D. Rosner
    • 1
  1. 1.University of Alabama at BirminghamUSA

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