Cerebral Perfusion Pressure Management of Head Injury
Previous work has demonstrated a causal relationship between unstable cerebral perfusion pressure (CPP) and the development of intracranial pressure (ICP) waves . The genesis of this CPP instability has usually (though not exclusively) been decrements in systemic arterial blood pressure (SABP). A simple model termed the “Vasodilatory Cascade” has been developed which demonstrates the interrelationships which lead to the complex interaction of SABP, ICP, and CPP . More importantly, the “Cascade” model in a more complex form leads directly to a model which helps interrelate both positive and negative aspects of many therapeutic modalities and their effect upon the whole system. From this understanding, a model upon which therapy  can be based has been developed and serves as the basis for the current report.
KeywordsTraumatic Brain Injury Emergency Medical Service Intracranial Hypertension Cerebral Perfusion Pressure Severe Head Injury
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