CT and MRI Evaluation of Traumatic Brain Edema and its Biochemical and Hystological Correlates
CT and MRI data allow the visualization of post-traumatic brain edema in patients. Investigations conducted over the past 10–15 years were largely experimental, some dealing with the clinical aspects of this problem including vasogenic edema (VE). It is known that CT shows VE as a perifocal zone of low density, but it is not clear whether CT and MRI can show the clearance of edematous fluid (EF) of vasogenic edema into the ventricular system (VS). Biochemical markers indicating the degree of brain parenchyma damage still remain to be identified. Blood brain barrier (BBB) permeability in severe head injury requires further study as well as the controversial role of pathogenic lipid peroxydation (LP).
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