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Sterol 26-Hydroxylase

  • K. Wikvall
Chapter
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 105)

Abstract

26-Hydroxylated derivatives participate in several pathways of cellular metabolism. The 26-hydroxylation in bile acid biosynthesis has been studied extensively. A 26-hydroxylation is involved also in vitamin D3 metabolism. By virtue of being potent inhibitors of enzymes in cholesterol biosynthesis, some 26-hydroxylated sterol derivatives, such as 26-hydroxycholesterol, have been ascribed a role in regulation of sterol biosynthesis.

Keywords

Bile Acid Liver Mitochondrion Cholic Acid Mitochondrial Cytochrome Cerebrotendinous Xanthomatosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 1993

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  • K. Wikvall

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