Sterol 26-Hydroxylase

  • K. Wikvall
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 105)


26-Hydroxylated derivatives participate in several pathways of cellular metabolism. The 26-hydroxylation in bile acid biosynthesis has been studied extensively. A 26-hydroxylation is involved also in vitamin D3 metabolism. By virtue of being potent inhibitors of enzymes in cholesterol biosynthesis, some 26-hydroxylated sterol derivatives, such as 26-hydroxycholesterol, have been ascribed a role in regulation of sterol biosynthesis.


Bile Acid Liver Mitochondrion Cholic Acid Mitochondrial Cytochrome Cerebrotendinous Xanthomatosis 
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© Springer-Verlag Berlin Heidelberg 1993

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  • K. Wikvall

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