Abstract
Cerebral blood flow velocities (CBFVs) were significantly higher in 41 infants of smoking mothers compared to 59 control infants although gestational age, birth weight, and systolic blood pressure were lower in infants exposed to smoke prenatally. We speculate that increased CBFVs in these neonates are due to disturbed prostanoid synthesis.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Abbreviations
- CBFV:
-
Cerebral blood flow velocity
- BP:
-
Arterial blood pressure
References
Ahlsten G, Ewald U, Tuvemu T (1987) Impaired vascular reactivity in newborns of smoking mothers. Acta Paediatr Scand 76: 248–253.
Bulterys MG, Greenland S, Kraus JF (1990) Chronic fetal hypoxia and sudden infant death syndrome: Interaction between maternal smoking and low hematocrit during pregnancy. Pediatrics 86: 535–540.
Chaudhuri G, Heglund B, Meirik O (1991) Endothelium-derived vasoactive substances in fetal placental vessels. Seminar Perinatol 15: 4–10.
Cnattingius S, Haglund B, Meirik O (1988) Cigarette smoke as risk factor for late fetal and early neonatal death. Br Med J 279: 258–261.
Dadak C, Leithner C, Sinzinger H (1981) Diminished prostacycline formation in umbilical arteries of babies born to women who smoke. Lancet i: 94.
Deeg KH, Rupprecht Th (1989) Pulsed Doppler sonographic measurement of normal values for the flow velocities in the intracranial arteries of healthy newboms. Pediatr Radiol 19: 71–78.
Leffler CB, Busija DW (1987) Arachidonic acid metabolites and perinatal cerebral hemodynamics. Seminar Perinatol 11: 31–42.
Lindblad A, Marsal K, Andersson K-E (1988) Effect of nicotine on human fetal blood flow. Obstet Gynecol 72: 371–382.
Merritt TA (1981). Smoking mothers affect little lives. Am J Dis Child 135: 501–502.
Morrow RJ, Ritchie JWK, Bull SB (1988) Maternal cigarette smoking: The effects on umbilical and uterine blood flow velocity. Am J Obstet Gynecol 159: 1069–1071.
Naeye RL, Peters EC (1984) Mental development of children whose mothers smoked during pregnancy and effects on the fetus. Obstet Gynecol 64: 601–607.
Nash JE, Persaud TVN (1988) Embryopathic risks of cigarette smoking. Exp Pathol 33: 65–73.
Perlman JM (1985) Neonatal cerebral blood flow velocity measurement. Clin Perinatol 15: 179–193.
Raju TNK (1991) Cerebral Doppler studies in the fetus and newborn infant. J Pediatr 119: 165–174.
Sokol JR, Drugan A, Evans M (1990) Substance abuse, smoking in pregnancy. In: Eden RD, Boehm FH (eds) Assessment and care of the fetus, physiological, clinical and medicolegal principles. Prentice-Hall International Inc., pp 687-691.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Abdul-Khaliq, H., Segerer, H., Obladen, M. (1992). Does Smoking During Pregnancy Alter Brain Perfusion in the Neonate? A Doppler Study. In: Neubert, D., Kavlock, R.J., Merker, HJ., Klein, J. (eds) Risk Assessment of Prenatally-Induced Adverse Health Effects. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77753-0_36
Download citation
DOI: https://doi.org/10.1007/978-3-642-77753-0_36
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-77755-4
Online ISBN: 978-3-642-77753-0
eBook Packages: Springer Book Archive