Abstract
The use of quantitative methods for risk assessment is not a routinely applied approach in teratology or other fields of reproductive toxicology, although in our opinion these methods should be used by researchers and accepted by regulatory agencies. One reason for this attitude is, that the usefulness of animal experiments for prenatal risk assessment is always under discussion. However, these experiments are, up till now, the only way to find and to exclude some of the risks for the unborn before a drug is marketed. If animal experiments are performed, they should be analysed using the best methods available.
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Meister, R. (1992). Aspects of Concentration-Response Analysis. In: Neubert, D., Kavlock, R.J., Merker, HJ., Klein, J. (eds) Risk Assessment of Prenatally-Induced Adverse Health Effects. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77753-0_17
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DOI: https://doi.org/10.1007/978-3-642-77753-0_17
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