Zusammenfassung
Vor 50 Jahren haben Harold Griffith und Enid Johnson erstmals ein Curarepräparat zur intraoperativen Muskelrelaxation eingesetzt. Die Autoren berichten über 25 erfolgreiche Operationen in flacher Cyclopropannarkose und Curarisierung. Das Relaxans, so heißt es euphorisch, sei frei von Nebenwirkungen gewesen. Eine neue Medikamentengruppe hatte Zugang zur Anästhesie gefunden. Muskelrelaxation im Abdominalbereich bedurfte künftig nicht mehr extrem hoher (z. T. lebensgefahrlicher) Dosen von Inhalationsanasthetika. Sie konnte bei flacher Allgemeinnarkose durch Gabe von Relaxanzien herbeigeführt werden. Das Prinzip der Komponentennarkose war entdeckt.
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© 1992 Springer-Verlag, Berlin Heidelberg New York
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Krieg, N., Hofmockel, R. (1992). Anwendung von kompetitiven Muskelrelaxanzien. In: Benad, G., Hofmockel, R. (eds) 50 Jahre Muskelrelaxanzien. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77725-7_6
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DOI: https://doi.org/10.1007/978-3-642-77725-7_6
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