Abstract
The submucous coat is a layer of strong but loose areolar tissue with some elastic fibres, lying between the muscularis mucosae and the muscularis externa; it is rich in mast cells, macrophages, lymphocytes, eosinophilic leucocytes and plasma cells. It forms a bed in which the vessels and nerves break up before entering the mucous membrane; consequently it contains arteries, veins, lymphatics and Meissner’s nerve plexuses. The plexuses form part of the autonomic nervous system and contain postganglionic sympathetic fibres as well as pre- and postganglionic parasympathetic fibres. The nerve cells are all parasympathetic.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Dembinski A, Gregory H, Konturek SJ, et al. Trophic action of epidermal growth factor on the pancreas and gastroduodenal mucosa in rats. J Physiol 1982, 325, 35–42.
Elder JB, Williams G, Lacey E, et al. Cellular localization of human urogastrone-epidermal growth factor. Nature 1978, 271, 466–467.
Ferri GL, Botti P, Biliotti G, et al. VIP, substance P and metenkaphalin immunoreactive innervation of the human gastrodudodenal mucosa and Brunner’s glands. Gut 1984, 25, 948–952.
Flemström G, Garner A. Some characteristics of duodenal epithelium. In: Mucus and Mucosa. Pitman, London 1984. Ciba Foundation Symposium 109, 94–108.
Florey HW, Harding HE. Further observations on the secretion of Brunner’s glands. J Path Bact 1934, 39, 255–276.
Fuse Y, Tsuchihashi Y, Takamasu M, et al. Thickness of Brunner’s glands and its clinical significance in duodenal ulcer disease. Scand J Gastroenterol 1990, 25, 165–172.
Gregory H. Isolation and structure of urogastrone and its relationship to epidermal growth factor. Nature 1975, 257, 325–327.
Griffith CA, Harkins HN. The role of Brunner’s glands in the intrinsic resistance of the duodenum to acid-pepsin digestion. Ann Surg 1956, 243, 160–172.
Heitz PU, Kasper M, Van Noorden S, et al. Immunohistochemical localization of urogastrone to human duodenal and submandibular glands. Gut 1978, 19, 408–413.
Hollenberg MD. Epidermal growth factor-urogastrone, a polypeptide acquiring hormonal status. Vitam Horm 1979, 37, 69–110.
Horton BT. Pyloric musculature, with special reference to pyloric block. Amer J Anat 1928, 41, 197–225.
Horton BT. Pyloric block with special reference to the musculature, myenteric plexus and lymphatic vessels. Arch Surg 1931, 22, 438–462.
Jamieson JK, Dobson JF. The lymphatic system of the stomach. Lancet 1907, 1, 1061–1066.
Kirkegaard P, Lundberg JM, Poulsen SS, et al. Vasoactive intestinal peptidergic nerves and Brunner’s gland secretion in the rat. Gastroenterology 1981, 81, 872–878.
Kirkegaard P, Skov Olsen P, Poulsen SS, et al. Epidermal growth factor inhibits cystamine induced duodenal ulcers. Gastroenterology 1983, 85, 1277–1283.
Kirkegaard P, Skov Olsen P, Poulsen SS, et al. Exocrine secretion of epidermal growth factor from Brunner’s glands: stimulation by VIP and acetylcholine. Regulatory Peptides 1983, 7, 367–372.
Kirkegaard P, Olsen PS, Nexo E, et al. Effect of vasoactive intestinal polypeptide and somatostatin on secretion of epidermal growth factor and bicarbonate from Brunner’s glands. Gut 1984, 25, 1225–1229.
Landboe-Christensen E. The duodenal glands of Brunner in man: their distribution and quantity. Acta Path Microbiol Scand 1944, Suppl 52, 11–267.
Skov Olsen P, Poulsen SS, Kirkegaard P. Adrenergic effects on secretion of epidermal growth factor from Brunner’s glands. Gut 1985, 26, 920–927.
Williams I. Closure of the pylorus. Brit J Rad 1962, 35, 653–670.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1993 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Keet, A.D. (1993). The Submucous Coat. In: The Pyloric Sphincteric Cylinder in Health and Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77708-0_4
Download citation
DOI: https://doi.org/10.1007/978-3-642-77708-0_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-77710-3
Online ISBN: 978-3-642-77708-0
eBook Packages: Springer Book Archive