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Abstract

As pointed out by Castleman (1936), there was a time when it was widely believed that gastric carcinoma did not invade the duodenum. In most of the earlier textbooks of surgery and surgical pathology it was stated that, while carcinoma of the stomach spread extensively in many directions by means of lymphatic and haematogenous metastases and through direct extension, it stopped abruptly at the pyloric ring. However, on reviewing the literature, Castleman (1936) collected 38 case reports of gastric carcinoma in which duodenal spread of the tumour had occurred. In the majority the extent of duodenal invasion was not more than 1–2 cm, but in isolated cases it could be as much as 5 cm. In view of these findings it was necessary to remove most of the first part of the duodenum in resections for gastric carcinoma.

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References

  1. Castleman B. Extension of gastric carcinoma into the duodenum. Ann Surg 1936, 103, 348–352.

    Article  PubMed  CAS  Google Scholar 

  2. Coller FA, Kay EB, McIntyre RS. Regional lymphatic metastases of carcinoma of the stomach. Arch Surg 1941, 43, 748–761.

    Article  Google Scholar 

  3. Dembinski A, Gregory H, Konturek SJ, et al. Trophic action of epidermal growth factor on the pancreas and gastroduodenal mucosa in rats. J Physiol 1982, 325, 35–42.

    PubMed  CAS  Google Scholar 

  4. Dixon CF, Stevens GA. Carcinoma of linitis plastica type involving the intestine. Ann Surg 1936, 103, 263–272.

    Article  PubMed  CAS  Google Scholar 

  5. Eker R. Carcinomas of the stomach: investigation of the lymphatic spread from gastric carcinomas after total and partial gastrectomy. Acta Chir Scand 1951, 101, 112–126.

    PubMed  CAS  Google Scholar 

  6. Eker R. Efskind J. Investigations on the intramural spread of gastric carcinoma. Acta Path Microbiol Scand 1952, 30, 371–383.

    Article  PubMed  CAS  Google Scholar 

  7. Eker R, Efskind J. The pathology and prognosis of gastric carcinoma. Acta Chir Scand 1960, Suppl 264, 1–182.

    Google Scholar 

  8. Elder JB, Williams G, Lacey E, et al. Cellular localization of human urogastrone-epidermal growth factor. Nature 1978, 271, 466–467.

    Article  PubMed  CAS  Google Scholar 

  9. Fernet P, Azar HA, Stout AR Intramural (tubal) spread of linitis plastica along the alimentary tract. Gastroenterology 1965, 48, 419–424.

    PubMed  CAS  Google Scholar 

  10. Ferri GL, Botti P, Biliotti G, et al. VIP, substance P and metenkephalin immunoreactive innervation of the human gastroduodenal mucosa and Brunner’s glands. Gut 1984, 25, 948–952.

    Article  PubMed  CAS  Google Scholar 

  11. Hawley PR, Westerholm P, Morson BC. Pathology and prognosis of carcinoma of the stomach. Brit J Surg 1970, 57, 877–883.

    Article  PubMed  CAS  Google Scholar 

  12. Heitz PU, Kasper M, Van Noorden S, et al. Immunohistochemical localization of urogast-rone to human duodenal and submandibular glands. Gut 1978, 19, 408–413.

    Article  PubMed  CAS  Google Scholar 

  13. Hollenberg MD. Epidermal growth factor-urogastrone, a polypeptide acquiring hormonal status. Vitam Horm 1979, 37, 69–110.

    Article  PubMed  CAS  Google Scholar 

  14. Joffe N, Goldman H, Antonioli DA. Transpyloric prolapse of polypoid gastric carcinoma. Gastroenterology 1977, 72, 1326–1330.

    PubMed  CAS  Google Scholar 

  15. Kirkegaard P, Lundberg JM, Poulsen SS, et al. Vasoactive intestinal peptidergic nerves and Brunner’s gland secretion in the rat. Gastroenterology 1981, 81, 872–878.

    PubMed  CAS  Google Scholar 

  16. Kirkegaard P, Skov Olsen P, Poulsen SS, et al. Exocrine secretion of epidermal growth factor from Brunner’s glands: stimulation by VIP and acetylcholine. Regulatory Peptides 1983, 7, 367–372.

    Article  PubMed  CAS  Google Scholar 

  17. Koehler RE, Hanelin LG, Laing FC, et al. Invasion of the duodenum by carcinoma of the stomach. Amer J Roent Rad Ther Nucl Med 1977, 128, 201–205.

    CAS  Google Scholar 

  18. Lee EY, Wang TC, Clouse RE, et al. Mucosal thickening adjacent to gastric malignancy: association with epidermal growth factor. Mod Pathol 1989, 2, 397–402.

    PubMed  CAS  Google Scholar 

  19. Lee EY, Wang TC, Clouse RE. Gastric carcinoma, epidermal growth factor and epidermal growth factor receptor (letter). Gastroenterology 1991, 100, 289.

    PubMed  CAS  Google Scholar 

  20. Majima S, Yamagucki I, Yoshida K, et al. Duodenal extension of carcinoma of the stomach. Tohoku J Exp Med 1964, 83, 159–167.

    Article  PubMed  CAS  Google Scholar 

  21. Ming SC. Tumors of the esophagus and stomach. Atlas of Tumor Pathology, Fascc 7, US Armed Forces Inst Path, Washington DC 1973, pp 200–201

    Google Scholar 

  22. Ming SC. Tumors of the esophagus and stomach. Atlas of Tumor Pathology, Fascc 7, US Armed Forces Inst Path, Washington DC 1973, pp 231–240.

    Google Scholar 

  23. Öhman U, Wetterfors J, Moberg A. Histologic grading of gastric cancer. Acta Chir Scand 1972, 138, 384–390.

    PubMed  Google Scholar 

  24. Paramanandhan TL. The duodenal spread of gastric carcinoma. Brit J Surg 1967, 54, 169–174.

    Article  PubMed  CAS  Google Scholar 

  25. Pfeiffer A, Rothbauer E, Wiebeeke B, et al. Increased epidermal growth factor receptors in gastric carcinoma. Gastroenterology 1990, 98, 961–967.

    Article  PubMed  CAS  Google Scholar 

  26. Skov Olsen P, Poulsen SS, Kirkegaard P. Adrenergic effect on secretion of epidermal growth factor from Brunner’s glands. Gut 1985, 26, 920–927.

    Article  Google Scholar 

  27. Zinninger MM, Collins WT. Extension of carcinoma of the stomach into the duodenum and esophagus. Ann Surg 1949, 130, 557–566.

    Article  Google Scholar 

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© 1993 Springer-Verlag Berlin Heidelberg

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Keet, A.D. (1993). Pyloric Carcinoma. In: The Pyloric Sphincteric Cylinder in Health and Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77708-0_33

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  • DOI: https://doi.org/10.1007/978-3-642-77708-0_33

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77710-3

  • Online ISBN: 978-3-642-77708-0

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