Abstract
Considerable progress in identifying cells and cytokines that regulate primary B cell differentiation has been made in the last few years, and it is now possible to present a model that identifies the stages at which various developmental signals act on B lineage cells. The formulation of such a scheme has been possible largely because of the use of various in vitro systems that allow the stromal cell dependent growth of B cells and their precursors and the application of molecular techniques to the analysis of cells in these cultures (Dorshkind 1990; Kincade et al. 1989).
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© 1992 Springer-Verlag Berlin Heidelberg
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Dorshkind, K., Narayanan, R., Landreth, K.S. (1992). Isolation and Characterization of a Stromal Cell Line. In: Potter, M., Melchers, F. (eds) Mechanisms in B-Cell Neoplasia 1992. Current Topics in Microbiology and Immunology, vol 182. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77633-5_2
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DOI: https://doi.org/10.1007/978-3-642-77633-5_2
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