Biology of Borrelia burgdorferi

  • V. Preac-Mursic
  • B. Wilske


Isolation and in vitro cultivation of Borrelia burgdorferi were first accomplished from Ixodes dammini ticks by Burgdorfer et al. (1982) and from patients by Benach et al. (1983) and Steere et al. (1983) in the Unites States. In Europe, identical microorganisms were detected and isolated from I. ricinus by Burgdorfer et al. (1983) and Barbour et al. (1983a) respectively. Isolates from patients were subsequently accomplished by Ackermann et al. (1984), Asbrink (1985), Asbrink et al. (1984) and Preac-Mursic et al. (1984). An important contribution had earlier been made by Kelly, who, in 1971 described a new medium permitting the cultivation of B. hermsii and other borreliae. Later on, Kelly’s medium was repeatedly modified especially for the cultivation of B. burgdorferi. The ability to grow B. burgdorferi in vitro has greatly facilitated studies concerning its morphological and biological characteristics.


Lyme Disease Borrelia Burgdorferi Lyme Borreliosis Linear Plasmid Plasmid Profile 
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© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • V. Preac-Mursic
  • B. Wilske

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