The Historical Road to the Discovery of Borrelia burgdorferi

  • W. Burgdorfer


This chapter is a historical account of events that eventually led to the discovery of the spirochetal etiology of the disease complex now known as Lyme spirochetosis or Lyme borreliosis. It is written to credit those whose names are rarely mentioned in today’s literature, despite the fact that they significantly contributed to one of the most exciting detective stories in microbiology. The earliest reference to a disease manifestation of Lyme borreliosis dates back to 1883 when the German physician Dr. Alfred Buchwald described a cutaneous syndrome as diffuse idiopathic skin atrophy. In 1902, Herxheimer and Hartmann introduced the name, acrodermatitis chronica atrophicans (ACA). This condition occurs commonly in Europe but rarely in the United States.


Lyme Disease Lyme Borreliosis Spotted Fever Erythema Migrans Tick Bite 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 1993

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  • W. Burgdorfer

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