Skip to main content
SpringerLink
Log in

Lyme Carditis

  • Chapter
Aspects of Lyme Borreliosis

Abstract

Lyme carditis can present as conduction or rhythm disturbances, (endo)myocarditis and pericarditis (with or without heart failure) (Steere et al. 1980; Bedell et al. 1981; Goldings and Jericho 1986; Hansen and Madsen 1986; Kapusta et al. 1986; Meyer and Swenson 1987; Hassler et al. 1987, 1988a,b; Lorcerie et al. 1987; Lefevre 1988; van der Linde et al. 1989). Lyme carditis may occur at any age and in either sex, although most European patients have been men (Table 2). Lyme borreliosis as an entity was described in 1977 by Steere et al., and, in 1980, Steere et al. characterized the cardiac manifestations of this disease. The first specific articles on Lyme carditis in Europe were reported in 1984 (Cornuau et al. 1984a,b; Houwerzijl et al. 1984). Many authors, however, had previously related cardiac complaints and abnormalities to other manifestations of Lyme borreliosis (Bannwarth 1941; Hopf 1966; Weber et al. 1983).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Allal J, Coisne D, Thomas P, Vieures C, Gallimard JF, Beeq-Giraudon B, Foullon P, Barraine R (1986) Manifestations cardiaque de la maladie de Lyme. Ann Med Interne (Paris) 137:372–374

    CAS  Google Scholar 

  • Alpert LI, Welch P, Fisher N (1985) Gallium-positive Lyme disease myocarditis. Clin Nucl Med 10:617

    Article  PubMed  CAS  Google Scholar 

  • Ballmer PE, Hany A (1988) Lyme-Karditis. Schweiz Med Wochenschr 118:358–362

    PubMed  CAS  Google Scholar 

  • Bannwarth A (1941) Chronische lymphocytäre Meningitis, entzündliche Polyneuritis und Rheumatismus. Arch Psychiatr Nervenkr 113:284–376

    Article  Google Scholar 

  • Beck G, Habicht GS, Benach JL, Coleman JL, Lysik RM, O’Brien RF (1986) A role for interleu- kin-1 in the pathogenesis of Lyme disease. Zentralbl Bakteriol Hyg (A) 263:133–136

    CAS  Google Scholar 

  • Bedell SE, Pastor BM, Cohen SI (1981) Symptomatic high grade heart block in Lyme disease. Chest 79:236–237

    Article  PubMed  CAS  Google Scholar 

  • Blaauw AAM, Braat S, van Santen-Hoeufft HM, van der Linden S J (1988) Cardiologische afwij- kingen bij patienten met Lyme-borreliose. Ned Tijdschr Geneeskd 132:2111–2114

    PubMed  CAS  Google Scholar 

  • Borgman H, Kumpf HP, Thess G, Schulze HJ (1989) Ein Fall von herzschrittmacherpflichtiger Lyme-Karditis. Z Gesamte Inn Med 44:247–248

    Google Scholar 

  • Cornuau C, Bardet M, Baudoin P, Daumas PL, Oblet B, Poirot G, Valois M (1984a) Bloc auri- culo-ventriculaire aigu, syncopal, au cours de la maladie de Lyme (letter). Presse Med 13:888

    PubMed  CAS  Google Scholar 

  • Cornuau C, Bernard M, Daumas PL, Oblet B, Poirot G, Valois M (1984b) Les manifestations cardiaques de la maladie de Lyme. A propos de deux observations. Ann Cardiol Angiol (Paris) 33:395–399

    CAS  Google Scholar 

  • De Koning J, Bosma RB, Hoogkamp-Korstanje JAA (1987) Demonstration of spirochetes in patients with Lyme disease with a modified silver stain. J Med Microbiol 23:261–267

    Article  PubMed  Google Scholar 

  • De Koning J, Hoogkamp-Korstanje JAA, van der Linde MR, Crijns HJGM (1989) Demonstration of spirochetes in cardiac biopsies of patients with Lyme disease. J Infect Dis 160:150–153

    Article  PubMed  Google Scholar 

  • Dournon E, Assous M, Fourcade C (1987) Clinical features of Lyme disease in France. In: Abstract book of the 27th interscience conference on antimicrobial agents and chemotherapy (ICAAC), New York, p 319, 1274

    Google Scholar 

  • Dunica S, Piette JC, Nassar N, Beaufils P (1986) Une nouvelle cause de bloc auriculo-ventricu- laire aigu transitoire: la maladie de Lyme. Arch Mal Coeur 79:1251–1255

    PubMed  CAS  Google Scholar 

  • Duray PH, Steere AC (1986) The spectrum of organ and systems pathology in human Lyme disease. Zentralbl Bakteriol Hyg (A) 263:169–178

    CAS  Google Scholar 

  • Fauchier JP, Cosnay P, Sirinelli A, Moquet B, Rabut H (1988) Myocardite de Lyme sans trouble conductifs auriculo-ventriculaires. Press Med 17:2036–2037

    CAS  Google Scholar 

  • Fumarolo D, Munno I, Marcuccio C, Miragliotta G (1986) Endotoxin-like activity associated with Lyme disease borrelia. Zentralbl Bakteriol Hyg (A) 263:142–145

    Google Scholar 

  • Goldings EA, Jericho J (1986) Lyme disease. Clin Rheum Dis 12:343–367

    PubMed  CAS  Google Scholar 

  • Habicht GS, Beck G, Benach JL, Coleman JL (1986) Borrelia burgdorferi lipopolysaccaride and its role in the pathogenesis of Lyme disease. Zentralbl Bakteriol Hyg (A) 263:137–141

    CAS  Google Scholar 

  • Habicht GS, Beck G, Benach JL (1987) Lyme disease. Sci Am 257:60–65

    Google Scholar 

  • Hansen K, Madsen JK (1986) Myocarditis associated with tickborneBorrelia burgdorferi infection. Lancet 1:1323–1324

    Article  PubMed  CAS  Google Scholar 

  • Hardin JA, Steere AC, Malawista SE (1979) Immune complexes and the evolution of Lyme arthritis: dissemination and localization of abnormal Clq binding activity. N Engl J Med 301:1358–1363

    Article  PubMed  CAS  Google Scholar 

  • Hassler D, Zipperle G, Ackermann R, Lembke U, Heinrich F (1987) Kardiale Beteiligung auch bei der Europaeischen Erythema-migrans-Borreliose? Dtsch Med Wochenschr 112:1506- 1508

    Article  PubMed  CAS  Google Scholar 

  • Hassler D, Geiselhardt B, Zipperle G, Zöller L, Sonntag HG, Heinrich F, Lang H, Wetzel H, Ackermann R (1988a) Internistische Aspekte der Lyme-Borreliose. Therapiewoche 38:2408- 2413

    Google Scholar 

  • Hassler D, Zipperle G, Ackermann R, Heinrich F (1988b) Die Borreliose. Z Allg Med 64:175–183

    Google Scholar 

  • Hopf HC (1966) Acrodermatitis Chronica Atrophicans (Herxheimer) und Nervensystem. Springer, Berlin Heidelberg New York, pp 70–71 (Monographien aus dem Gesamtgebiete der Neurologie und Psychiatrie, vol 114)

    Google Scholar 

  • Houwerzijl J, Root JJ, Hoogkamp-Korstanje JAA (1984) A case of Lyme disease with cardiac involvement in the Netherlands (letter). Infection 12:358

    Article  Google Scholar 

  • Jacobs JC, Rosen JM, Szer IS (1984) Lyme myocarditis diagnosed by gallium scan. J Pediatr 105:950–952

    Article  PubMed  CAS  Google Scholar 

  • Kapusta P, Fauchier JP, Cosnau P, Huguet R, Grezard O, Rouesnel P (1986) Troubles conductifs sino-auriculaires et auriculo-ventriculaires de la maladie de Lyme. A propos de deux observations. Arch Mal Coeur 79:1361 -1366

    PubMed  CAS  Google Scholar 

  • Kuiper H, De Jongh BM, Senden PJ (1988) Pacemaker-implantatie wegens totaal atrioventricu- lair block bij Lyme-borreliose. Ned Tijdschr Geneeskd 132:2109–2111

    PubMed  CAS  Google Scholar 

  • Laperrouza C (1985) La boiréliose de Burgdorfer ou maladie de Lyme: expérience en zone endémique. Med Hyg 43:2885–2896

    Google Scholar 

  • Lavaud P, Etienne J, Chamot E, Atallah G, Moleur P, Brun Y, Touboul P (1985) Bloc auriculo- ventriculaire aigu associé une maladie de Lyme. Un cas confirmé par sérologie (letter). Presse Med 14:2020

    PubMed  CAS  Google Scholar 

  • Lefèvre T (1988) Quel est votre diagnostic? Concours Med 110:2473–2475

    Google Scholar 

  • Lorcerie B, Boutron MC, Portier H, Beuriat P, Ravisy J, Martin F (1987) Manifestations pericar- dique de la maladie de Lyme. Ann Med Interne (Paris) 138:601–603

    CAS  Google Scholar 

  • Marcus LC, Steere AC, Duray PH, Anderson AE, Mahoney EB (1985) Fatal pancarditis in a patient with coexistent Lyme disease and babesiosis: demonstation of spirochetes in the myocardium. Ann Intern Med 103:374–376

    PubMed  CAS  Google Scholar 

  • Mayer W, Kleber FX, Wilske B, Preac-Mursic V, Maciejewski W, Sigl H, Holzer E, Doering W (1989) Persistent atrioventricular block in Lyme disease. Klin Wochenschr 68:431–435

    Article  Google Scholar 

  • Meyer LK, Swenson DB (1987) Lyme carditis: high-grade heart block in Lyme disease. Minn Med 70:345–346

    PubMed  CAS  Google Scholar 

  • Muhlemann MF, Wright DJ (1987) Emerging pattern of Lyme disease in the United Kingdom and Irish Republic. Lancet 1:260–262

    Article  PubMed  CAS  Google Scholar 

  • O’Connell JB, Henkin RE, Robinson JA, Subramanian R, Path MRC, Scanion PJ, Gunnar RM (1984) Gallium-67 imaging in patients with dilated cardiomyopathy and biopsy-proven myocarditis. Circulation 70:58–62

    Article  PubMed  Google Scholar 

  • Olson LJ, Okafor EC, Clements IP (1986) Cardiac involvement in Lyme disease: manifestations and management. Mayo Clin Proc 61:745–749

    PubMed  CAS  Google Scholar 

  • Ponsonnaille J, Citron B, Karsenty B, DAgrosa MC, Peyselon P, Veyre A, Gras H (1986) Myocardite aiguë au cours d’un syndrome de Lyme. Intérêt de la scintigraphic myocardique au gallium 67. Arch Mal Coeur 79:1946–1950

    PubMed  CAS  Google Scholar 

  • Reznick JW, Braunstein DB, Walsh RL, Smith CR, Wolfson PM, Gierke LW, Gorelkin L, Chandler FW (1986) Lyme carditis. Electrophysiologic and histopathologic study. Am J Med 81:923–927

    Article  PubMed  CAS  Google Scholar 

  • Rienzo RJ, Morel DE, Prager D, Barron L, Post R (1987) Gallium avid Lyme myocarditis. Clin Nucl Med 12:475–476

    Article  PubMed  CAS  Google Scholar 

  • Roelli H, Angehrn W, Reutter FW (1988) Atrio-ventrivuläre Blockierung bei Lyme-Karditis. Schweiz Med Wochenschr 118 (Suppl 23):6

    Google Scholar 

  • Roelli H, Angehrn W, Reutter FW (1988) Atrio-ventriculäre Blockierung bei Lyme-Karditis. Schweiz Med Wochenschr 119:81–83

    Google Scholar 

  • Satz N, Ott A, Knoblauch M (1986) Die Erythema-migrans-Krankheit. Das klinische Spektrum der Infektion mit Borrelia burgdorferi. Schweiz Med Wochenschr 116:763–769

    PubMed  CAS  Google Scholar 

  • Schmidt R, Kabatzki J, Härtung S, Ackermann R (1985) Erythema-migrans-Borreliose in der Bundesrepublik Deutschland: Epidemiologie und klinisches Bild. Dtsch Med Wochenschr 110:1803–1807

    Article  PubMed  CAS  Google Scholar 

  • Schott B (1985) Erytheme de Lipschütz avec atteinte cardiaque. A propos d’un cas: étiology méconne de BAV paroxystique. Synthèse et rapport avec la maladie de Lyme aux USA. Thesis, Louis Pasteur University, Strasbourg, France

    Google Scholar 

  • Stanek G, Flamm H, Groh V, Hirschl A, Kristoferitsch W, Neumann R, Schmutzhard E, Wewalka G (1986) Epidemiology of Borrelia infections in Austria. Zentralbl Bakteriol Hyg (A) 263:442–449

    Google Scholar 

  • Stanek G, Klein J, Bittner R, Glogar D (1990) Isolation of Borrelia burgdorferi from the myocardium of a patient with longstanding cardiomyopathy. N Engl J Med 322:249–252

    Article  PubMed  CAS  Google Scholar 

  • Steere AC, Malawista SE, Sriydman DR, Shope RE, Andiman WA, Ross MR, Steele FM (1977) Lyme arthritis: an epidemic of oligoarticular arthritis in children and, adults in three Connecticut communities. Arthritis Rheum 20:7–17

    Article  PubMed  CAS  Google Scholar 

  • Steere AC, Batsford WP, Weinberg M, Alexander J, Berger HJ, Wolfson S, Malawista SE (1980) Lyme carditis: cardiac abnormalities of Lyme disease. Ann Intern Med 93:8–16

    PubMed  CAS  Google Scholar 

  • Steurer J, Bansky G, Greminger P, Siegenthaler W (1987) Acrodermatitis chronica atrophicans und Lymesche Erkrankung. Internist 28:693–697

    PubMed  CAS  Google Scholar 

  • Trevison G, Crovato F, Marcuccio C, Fumarola D, Scarpa C (1986) Lyme disease in Italy. Zentralbl Bakteriol Hyg (A) 263:459–463

    Google Scholar 

  • Vacher D, Lusson JR, Peyselon P, Kantelip B, Veyre A, Cassagnes J (1987) La myocardite de Lyme: intérêt des examens scintigraphiques (Gallium 67 et Thallium 201) et de la biopsie endomyocardique (à propos de deux cas). Coeur 18:374–379

    Google Scholar 

  • Van der Linde MR, Crijns HJGM, Lie Kl (1989) Transient complete atrioventricular block in Lyme disease. Chest 96:219–221

    Article  PubMed  Google Scholar 

  • Van der Linde MR, Crijns HJGM, de Koning J, Hoogkamp-Korstanje JAA, de Graaf JJ, Piers DA, van der Galien A, Lie KÏ (1990) Range of atrioventricular conduction disturbances in Lyme borreliosis: a report of 4 cases and review of other published reports. Br Heart J 63:162–168

    Article  PubMed  Google Scholar 

  • Veyssier P, Davous N, Kalousstian E, Maitre B, Lallement PY, Serret A (1987) Atteintes cardiaques au cours de la maladie de Lyme. Deux observations. Rev Med Interne 8:357–360

    Article  PubMed  CAS  Google Scholar 

  • Vieyres C, Allai J, Coisne D, Amiel A, Barraine R (1987a) Manifestations cardiaques de la maladie de Lyme. Mises Jour Cardiol 16:13–21

    Google Scholar 

  • Vieyres C, Allai J, Coisne D, Thomas Ph, Neau JP, Breux JP (1987b) Aspects européens de la maladie de Lyme. Huit cas. Press Med 16:59–62

    CAS  Google Scholar 

  • Weber K, Puzik A, Becker T (1983) Erythema-migrans-Krankheit. Beitrag zur Klinik und Beziehung zur Lyme-Krankheit. Dtsch Med Wochenschr 108:1182–1190

    Article  PubMed  CAS  Google Scholar 

  • Wunderlich E, Thess G, Hetze A, Witzleb W, Schmidt PKH (1988) Lyme-Borreliose - eine mögliche Ursache von atrioventrikulären (AV-)Blockierungen. Z Kardiol 77:256–258

    PubMed  CAS  Google Scholar 

Download references

Authors
  1. M. R. van der Linde
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. E. Ballmer
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Rosenstr.6, 8000, München 2, Germany

    Klaus Weber (Dermatologist in Private Practice) (Dermatologist in Private Practice)

  2. Laboratory of Vectors and Pathogens, Rocky Mountain Laboratories, Department of Health and Human Services, Public Health Service,National Institutes of Health, National Institute of Allergy and Infectious Diseases, 59840, Hamilton, MT, USA

    Willy Burgdorfer Ph.D.,M.D.(h.c.)

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

van der Linde, M.R., Ballmer, P.E. (1993). Lyme Carditis. In: Weber, K., Burgdorfer, W., Schierz, G. (eds) Aspects of Lyme Borreliosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77614-4_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-77614-4_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77616-8

  • Online ISBN: 978-3-642-77614-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation