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Prognosis and Management

  • E. M. Gilbert
  • A. Di Lenarda
  • J. B. O’Connell

Abstract

Dilated cardiomyopathy is a disease of unknown etiology that principally affects the myocardium [1]. The diagnosis of dilated cardiomyopathy is established by the presence of left ventricular dilatation and systolic dysfunction in the absence of congenital, coronary, valvular, or pericardial heart disease [2]. In some patients the development of dilated cardiomyopathy is associated with clinical factors such as alcoholism, pregnancy or a family history of cardiomyopathy [1,2]. However, dilated cardiomyopathy is distinct from specific heart muscle disease (“secondary myocardial disease”), which occurs with a specific systemic disorder that may be metabolic, collagen-vascular, infiltrative, neuromuscular, inflammatory, or neoplastic in origin [1, 2] (see Chap. 1). There are currently no specific gross anatomic, histologic, or ultrastructural morphologic features which can differentiate dilated cardiomyopathy from other causes of heart failure [3]. Since dilated cardiomyopathy is defined clinically, it is likely that several specific etiologies are responsible for this condition. It is therefore not surprising that patients with dilated cardiomyopathy have a heterogeneous clinical presentation and prognosis.

Keywords

Left Ventricular Ejection Fraction Cardiac Index Dilate Cardiomyopathy Angiotensin Converting Enzyme Inhibitor Endomyocardial Biopsy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • E. M. Gilbert
  • A. Di Lenarda
  • J. B. O’Connell

There are no affiliations available

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