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Pathophysiologie von Motilitätsstörungen im oberen Gastrointestinaltrakt

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Störungen der Motilität des oberen Gastrointestinaltraktes

Zusammenfassung

Der intakte Magen besteht aus 2 aufeinander abgestimmten Funktionseinheiten [31]. Der proximale Magen akkommodiert postprandial [12], indem sich das Magenvolumen reflektorisch an das Volumen des aufgenommenen Speisebreis ohne eine signifikante Erhöhung des intragastralen Drucks anpaßt. Durch anhaltende tonische Funduskontraktion erfolgt über diese Regulation des intragastralen Drucks dann eine rasche, exponentielle Entleerung flüssiger Nahrungsbestandteile [25]. Die Entleerungsgeschwindigkeit von Flüssigkeiten wird darüber hinaus vom Flußwiderstand im antropylorischen Segment und proximalen Duodenum sowie von der intakten Koordination dieser Abschnitte bestimmt.

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Literatur

  • Arndorfer RC, Stef JJ, Dodds WJ et al. (1977) Improved infusion system for intraluminal esophageal manometry. Gastroenterology 73: 23–27

    PubMed  CAS  Google Scholar 

  • Azpiroz F, Malagelada JR (1985) Physiological variations in canine gastric tone measured by an electronic barostat. Am J Physiol 248: G229–237

    PubMed  CAS  Google Scholar 

  • Azpiroz F, Malagelada JR (1985) The role of vagal input in the control of gastric tone. Gastroenterology 88: 1312

    Google Scholar 

  • Azpiroz F, Malagelada JR (1987) Gastric tone measured by an electronic barostat in healthy and postsurgical gastroparesis. Gastroenterology 92: 934–943

    PubMed  CAS  Google Scholar 

  • Brady PG, Richardson R (1977) Gastric bezoar formation secondary to gastroparesis diabeticorum. Arch Int Med 137: 1729

    Article  CAS  Google Scholar 

  • Camilleri M, Malagelada JR (1984) Abnormal intestinal motility in diabetics with the gastroparesis syndrome. Eur J Clin Invest 14: 420–427

    Article  PubMed  CAS  Google Scholar 

  • Camilleri M, Malagelada JR, Kao PC et al. (1986) Gastric and autonomic responses to stress in functional dyspepsia. Dig Dis Sci 31: 1169–1177

    Article  PubMed  CAS  Google Scholar 

  • Camilleri M, Colemont LC, Phillips SF et al. (1989) Human gastric emptying and colonic filling of solids characterized by a new method. Am J Physiol 257: G284–290

    PubMed  CAS  Google Scholar 

  • Camilleri M (1989) Jejunal manometry in distal subacute mechanical obstruction: significance of prolonged simultaneous contractions. Gut 30: 468–475

    Article  PubMed  CAS  Google Scholar 

  • Camilleri M (1990) Disorders of gastrointestinal motility in neurologic diseases. Mayo Clin Proc 65: 825–846

    PubMed  CAS  Google Scholar 

  • Campell IW, Heading RC, Tothill P et al. (1977) Gastric emptying in diabetic autonomic neuropathy. Gut 18: 462–467

    Article  Google Scholar 

  • Cannon WB, Lieb CW (1911) The receptive relaxation of the stomach. Am J Physiol 29: 267–273

    Google Scholar 

  • Carlson HC, Code CF, Nelson RA (1966) Motor action of the canine gastroduodenal junction: a cineradiographic, pressure and electric study. Am J Dig Disease 11: 155–172

    Article  CAS  Google Scholar 

  • Code CF, Marlett JA (1975) The interdigestive myo-electric complex of the stomach and small bowel of dogs. J Physiol (London) 246: 289–309

    CAS  Google Scholar 

  • Colemont LJ, Camilleri M (1989) Chronic intestinal pseudo-obstruction: diagnosis and treatment. Mayo Clin Proc 64: 60–70

    PubMed  CAS  Google Scholar 

  • Cottrell CR, Sninsky CA, Martin JL et al. (1982) Are alterations in gastrointestinal motility responsible for previously unexplained nausea, vomiting, and abdominal pain? Dig Dis Sci 27: 650

    Google Scholar 

  • Dot evali G, Fagersberg SE, Langer L et al. (1972) Vagal function in patients with diabetic neuropathy. Acta Med Scand 191: 21–24

    Google Scholar 

  • Dozois RR, Kelly KA, Code CF (1971) Effect of distal antrectomy on gastric emptying of liqids and solids. Gastroenterology 61: 675–681

    PubMed  CAS  Google Scholar 

  • Drosman DA, Grant Thompson W, Talley NJ et al. (1990) Identification of subgroups of functional gastrointestinal disorders. Gastroenterol Intern 3: 159–172

    Google Scholar 

  • Dudley HAF, Sinclair ISR, McLaren IF et al. (1958) Intestinal pseudoobstruction. JR Coll Surg Edinburgh 3: 206–217

    CAS  Google Scholar 

  • Faulk DL, Anuras S, Christensen J (1978) Chronic intestinal pseudoobstruction. Gastroenterology 74: 922–931

    PubMed  CAS  Google Scholar 

  • Feldman M, Corbett DB, Ramsey EJ et al. (1979) Abnormal gastric function in longstanding, insulin-dependent diabetic patients. Gastroenterology 77: 12–17

    PubMed  CAS  Google Scholar 

  • Feldman M, Smith JH, Simon TR (1984) Gastric emptying of solid radiopaque markers: studies in healthy subjects and diabetic patients. Gastroenterology 87: 805–902

    Google Scholar 

  • Greydanus MP, Carnilleri M (1989) Abnormal postcibal antral and small bowel motility due to neuropathy and myopathy in systemic sclerosis. Gastroenterology 96: 110–115

    PubMed  CAS  Google Scholar 

  • Hinder RA, Kelly KA (1977) Canine gastric emptying of solids and fluids. Am J Physiol 233: E335-E340

    PubMed  CAS  Google Scholar 

  • Horowitz M, Harding PE, Chatterton BE et al. (1985) Acute and chronic effects of domperidone on gastric emptying in diabetic autonomic neuropathy. Dig Dis Sci 30: 1–9

    Article  PubMed  CAS  Google Scholar 

  • Hosking DJ, Moody F, Stewart IM et al. (1975) Vagal impairment of gastric secretion in diabetic autonomic neuropathy. Br Med J 2: 588–590

    Article  PubMed  CAS  Google Scholar 

  • Kalbasi H, Hudson FR, Herrmig A et al. (1975) Gastric emptying following vagotomy and antrectomy and proximal gastric vagotomy. Gut 16: 509–513

    Article  PubMed  CAS  Google Scholar 

  • Karlstrom L, Kelly KA (1989) Roux-Ygastrectomy for chronic gastric atony. Am J Surg 157: 44–49

    Article  PubMed  CAS  Google Scholar 

  • Kassander P (1958) Asymptomatic gastric retention in diabetics (gastroparesis diabeticorum). Ann Intern Med 48: 797–812

    PubMed  CAS  Google Scholar 

  • Kelly KA (1980) Gastric emptying of liquids and solids: roles of proximal and distal stomach. Am J Physiol 239: G71-G76

    PubMed  CAS  Google Scholar 

  • Kraft RO, Fry WJ, DeWeeze MS (1964) Postvagotomy gastric atony. Arch Surg 88: 865–871

    PubMed  CAS  Google Scholar 

  • Krishnamurthy S, Schuffler MD (1987) Pathology of neuromuscular disorders of the small intestine and colon. Gastroenterology 93: 610–639

    PubMed  CAS  Google Scholar 

  • Kristensson K, Nordborg C, Olsson Y et al. (1971) Changes in the vagus nerve in diabetes mellitus. Acta Pathol Microbiol Scand 79: 684–685

    CAS  Google Scholar 

  • Layer P, Demol P, Hotz J et al. (1986) Gastroparesis after radiation: successful treatment with carbachol. Dig Dis Sci 31: 1377–1386

    Article  PubMed  CAS  Google Scholar 

  • Loo FD, Palmer DW, Soergel KH et al. (1984) Gastric emptying in patients with diabetes mellitus. Gastroenterology 86: 485–494

    PubMed  CAS  Google Scholar 

  • Malagelada JR, Carter SE, Brown ML et al. (1980) Radiolabelled fiber: a physiological marker for gastric emptying and intestinal transit of solids. Dig Dis Sci 25: 81–87

    Article  PubMed  CAS  Google Scholar 

  • Malagelada JR, Rees WDW, Mazotta LJ et al. (1980) Gastric motor abnormalities in diabetic and postvagotomy gastroparesis: effect of metoclopramide and betanechol. Gastroenterology 78: 286–293

    PubMed  CAS  Google Scholar 

  • Malagelada JR (1981) Gastric, pancreatic, and biliary responses to a meal. In: Johnson LR, Christensen J, Grossman MI et al. (eds) Physiology of the gastrointestinal tract, vol 2. Raven, New York, pp 893–924

    Google Scholar 

  • Malagelada JR, Robertson JS, Brown ML et al. (1984) Intestinal transit of solid and liquid components of a meal in health. Gastroenterology 87: 1255–1263

    PubMed  CAS  Google Scholar 

  • Malagalada JR, Stangheilini V (1985) Manometric evaluation of functional upper gut symptoms. Gastroenterology 88: 1223–1231

    Google Scholar 

  • Malagelada JR, Camilleri M, Stangheilini V (1986) Manometric diagnosis of gastrointestinal motility disorders.Thieme, Stuttgart New York

    Google Scholar 

  • Mearin F, Camilleri M, Malagelada JR (1986) Pyloric dysfunction in diabetics with recurrent nausea and vomiting. Gastroenterology 90: 1919–1925

    PubMed  CAS  Google Scholar 

  • Meeroff JC, Schreiber DS, Trier JS et al. (1980) Abnormal gastric motor function in viral gastroenteritis. Ann Intern Med 92: 370–373

    PubMed  CAS  Google Scholar 

  • Meyer JH, Dressman, Fink A et al. (1985) Effect of size and density on canine gastric emptying of nondigestible solids. Gastroenterology 89: 805–813

    PubMed  CAS  Google Scholar 

  • Meyer JH, Elashoff J, Porter-Fink Vet al. (1988) Human postprandial gastric emptying of 1–3 millimeter spheres. Gastroenterology 94: 1315–1325

    PubMed  CAS  Google Scholar 

  • Mroz CT, Kelly KA (1977) The role of the extrinsic antral nerves in the regulation of gastric emptying. Surg Gynecol Obstet 145: 369–377

    PubMed  CAS  Google Scholar 

  • Rees WDW, Miller LJ, Malagelada JR (1980) Dyspepsia, antral motor function, and gastric stasis of solids. Gastroenterology 78: 360–365

    PubMed  CAS  Google Scholar 

  • Rohrmann CA Jr, Ricci MT, Krishnamurthy S et al. (1984) Radiologie and histologic differentiation of neuromuscular disorders in the gastrointestinal tract: visceral myopathies, visceral neuropathies, and progressive systemic sclerosis. Am J Radiol 143: 933–941

    Google Scholar 

  • Schade RR, Dugas MC, Lhotsky DM et al. (1985) Effect of metoc- lopramide on gastric liquid emptying in patients with diabetic gastro- paresis. Dig Dis Sci 30: 10–15

    Article  PubMed  CAS  Google Scholar 

  • Schuffler MD, Rohrmann CA, Chaffee FG et al. (1981) Chronic intestinal pseudoobstruction: a report of 27 cases and a review of the literature. Medicine 60: 173–196

    Article  PubMed  CAS  Google Scholar 

  • Schuffler MD (1988) Neuromuscular disorders and intestinal pseudoobstruction. In: Gitwick (ed) Principles and practice of gastroenterology and hepatology, chap 24. Elsevier, Amsterdam New York, pp 317–322

    Google Scholar 

  • Schuster R, Ferenci P, Schmidbauer M et al. (1989) Intestinal neuronal degeneration in a patient with chronic intestinal pseudoobstruction. Dig Disease Sci 34: 123–128

    Article  CAS  Google Scholar 

  • Smith B (1974) Neuropathy of the oesophagus in diabetes mellitus. J Neurol Neurosurg Psychiat 37: 1151–1154

    Article  PubMed  CAS  Google Scholar 

  • Snape WJ, Battle WM, Schwartz SS et al. (1982) Metoclopramide to treat gastroparesis due to diabetes mellitus. A doubble-blind controlled trial. Ann Intern Med 96: 444–446

    PubMed  Google Scholar 

  • Stangheilini V, Camilleri M, Malagelada JR (1987) Chronic idiopathic pseudoobstruction: clinical and intestinal manometric findings. Gut 28: 5–12

    Article  Google Scholar 

  • Telander RL, Morgan KG, Kreulen DL et al. (1978) Human gastric atony with tachygastria and gastric retention. Gastroenterology 75: 497–501

    PubMed  CAS  Google Scholar 

  • Thomforde GM, Brown ML, Malagelada JR (1985) Practical solid and liquid phase markers for studying gastric emptying in man. J Nucl Med 13: 11–14

    Google Scholar 

  • Thompson DG, Wingate DL, Archer L et al. (1980) Normal patterns of human upper small bowel activity recorded by prolonged radiote- lemetry. Gut 21: 500–506

    Article  PubMed  CAS  Google Scholar 

  • Wilbur BG, Kelly KA (1973) Effect of proximal gastric, complete gastric, and truncal vagotomy on canine gastric electric activity, motility, and emptying. Ann Surg 178: 295–302

    Article  PubMed  CAS  Google Scholar 

  • Wilbur BG, Kelly KA, Code CF (1974) Effect of gastric fundectomy on canine gastric electrical and motor activity. Am J Physiol 226: 1445–1449

    PubMed  CAS  Google Scholar 

  • Zitomer BR, Gramm HF, Kozak GP (1968) Gastric neuropathy in diabetes mellitus: clinical and radiological observations. Metabolism 17: 199–211

    Article  PubMed  CAS  Google Scholar 

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Authors
  1. M. von der Ohe
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Editors and Affiliations

  1. Abteilung Gastroenterologie, Zentrum für innere Medizin, Universitäts-Klinikum Essen, Hufelandstraße 55, 4300, Essen 1, Deutschland

    Harald Goebell (Direktor) & Peter Layer (Direktor) & 

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© 1992 Springer-Verlag Berlin Heidelberg

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von der Ohe, M. (1992). Pathophysiologie von Motilitätsstörungen im oberen Gastrointestinaltrakt. In: Goebell, H., Layer, P. (eds) Störungen der Motilität des oberen Gastrointestinaltraktes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77589-5_2

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  • DOI: https://doi.org/10.1007/978-3-642-77589-5_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-55584-1

  • Online ISBN: 978-3-642-77589-5

  • eBook Packages: Springer Book Archive

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