A Clinical Study of Familial Cancer in Japan
A high incidence of a particular cancer in a family points to the involvement of genetic factors. Hereditary tumours include colorectal cancer based on familial adenomatous polyposis (FAP) and medullary carcinoma of the thyroid in MEN type 2. The mode of inheritance of these cancers has been clarified. It is also known that some family lines have a high incidence of morphologically ordinary types of cancer.
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