A Clinical Study of Familial Cancer in Japan
A high incidence of a particular cancer in a family points to the involvement of genetic factors. Hereditary tumours include colorectal cancer based on familial adenomatous polyposis (FAP) and medullary carcinoma of the thyroid in MEN type 2. The mode of inheritance of these cancers has been clarified. It is also known that some family lines have a high incidence of morphologically ordinary types of cancer.
KeywordsBreast Cancer Gastric Cancer Colorectal Cancer Multiple Cancer Familial Breast Cancer
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- 1.Utsunomiya J et al: Familial large bowel cancer. In: Decosse JJ (ed) Clinical Surgery International: Large Bowel Cancer. Churchill Livingstone, New York 1981 pp 16–33Google Scholar
- 2.Nomizu T et al: Clinical investigation of familial clustering of cancer. Jpn J Cancer Clin 1986 (32):485–492 (in Japanese with English abstract)Google Scholar
- 3.Kunitomo K et al: HNPCC in Japan. In: Third Meeting of the ICG-HNPCC, and 5th International Symposium on Colorectal Cancer, Turin, Italy, September 1991Google Scholar
- 5.Nomizu T et al: Breast cancer prone family: Clinical study of familial breast cancer. Jpn J Cancer Clin 1987 (33):477–481 (in Japanese with English abstract)Google Scholar
- 6.Nomizu T et al: Clinical study of breast cancer patients with family history. Jpn J Breast Cancer 1987 (2):435–439 (in Japanese with English abstract)Google Scholar