Cancer Prevention Through Genetic Counselling

  • Hansjakob Müller
Conference paper
Part of the ESO Monographs book series (ESO MONOGRAPHS)


Several types of familial cancer can be prevented from progressing to advanced stages by regular surveillance of the person at risk [1] and hence by the early treatment of the developing neoplasia. Genetic counselling of such patients and their relatives is, therefore, an important task which often remains unrecognised. This is especially true for the common familial forms of cancer such as breast and colorectal cancer which aggregate in the families of about 5% of all patients according to the rules of autosomal-dominant inheritance [2]. The prevention of cancer is promising, especially for the familial forms because persons at risk are motivated to take preventive measures, in particular when they can be identified with certainty and counselled with concrete information [3].


Genetic Counselling Family Doctor Familial Form Familial Cancer Reduce Life Expectancy 
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  1. 1.
    Müller Hj and Vasen HFA: Prävention familiärer Tumorkrankheiten durch genetische Beratung und Frühdiagnostik. Schweiz Med Wschr 1990 (120):1451–1460PubMedGoogle Scholar
  2. 2.
    Müller Hj: Dominant inheritance of human cancer. Anticancer Res 1990 (10):505–512PubMedGoogle Scholar
  3. 3.
    Müller Hj: Genetic counselling and cancer. In: Weber W, Laffer UT, Dürig M (eds) Hereditary Cancer and Preventive Surgery. Karger, Basel 1990 pp 12–18Google Scholar
  4. 4.
    Müller Hj: Familial cancer in Basel: some aspects. In: Müller Hj, Weber W (eds) Familial Cancer. Karger, Basel 1985 pp 1–5Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • Hansjakob Müller
    • 1
  1. 1.Research Group of Human Genetics, Department of ResearchKantonsspitalBaselSwitzerland

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