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Familial Cancer Control pp 45–49Cite as

Cost-Benefit Implications in the Surveillance of Lynch Syndrome Subjects

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Part of the book series: ESO Monographs ((ESO MONOGRAPHS))

Abstract

Hereditary diseases, especially tumours of the gastrointestinal (Gl) tract, are gaining interest throughout the world [1,2]. They represent a unique model for the understanding of the aetiology of cancer and its biological behaviour, enabling us to introduce preventive strategies and possibly newer, more sophisticated therapies which are currently being searched for by molecular biologists [3].

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References

  1. Lynch HT, Lanspa SJ, Smyrk TC, Fitzgibbons RJ, Watson P, Boman BM, Lynch JF and Cristofaro G: Historical and natural cancer history facets of the Lynch Syndromes. In: Utsunomiya J and Lynch HT (eds) Hereditary Colon Cancer. Springer Verlag, Tokyo, Berlin, Heidelberg, New York, London, Paris, Hong Kong, Barcelona 1990 pp 17–25

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  2. Cristofaro G, Lynch HT, Caruso ML, Attolini A et al: New phenotypic aspects in a family with Lynch Syndrome II. Cancer 1987 (60):51–58

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  3. Vogelstein B, Fearon ER, Hamilton SR, Bodmer WF, Jass JR, Jeffreys AJ, Lucibello FC, Patel I and Rider SH: Genetic alterations during colorectal tumor development. N Engl J Med 1988 (319):525–532

    Article  PubMed  CAS  Google Scholar 

  4. Lynch HT: Frequency of hereditary nonpolyposis colorectal cancer. Gastroenterology 1986 (90):486–492

    PubMed  CAS  Google Scholar 

  5. Mecklin JP: Frequency of hereditary colorectal cancer. Gastroenterology 1987 (93):1021–1025

    PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Hereditary Gastrointestinal Cancer Prevention Centre, Brindisi, Italy

    Giuseppe Cristofaro

  2. Chamber of Commerce, Brindisi, Italy

    Eupremio Carrozzo (Head of the Statistics Office)

  3. British Consulate, Brindisi, Italy

    Frederick Gentile

  4. Vth Surgical Clinic, Department of Endoscopy, “La Sapienza” University, Rome, Italy

    Emilio Di Giulio

Authors
  1. Giuseppe Cristofaro
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  2. Eupremio Carrozzo
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  3. Frederick Gentile
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  4. Emilio Di Giulio
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Editor information

Editors and Affiliations

  1. Swiss Cancer League, Monbijoustraße 61, 3001, Bern, Switzerland

    Walter Weber (Medical Oncology Scientific Secretary) (Medical Oncology Scientific Secretary)

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© 1992 Springer-Verlag Berlin Heidelberg

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Cite this paper

Cristofaro, G., Carrozzo, E., Gentile, F., Di Giulio, E. (1992). Cost-Benefit Implications in the Surveillance of Lynch Syndrome Subjects. In: Weber, W. (eds) Familial Cancer Control. ESO Monographs. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77582-6_11

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  • DOI: https://doi.org/10.1007/978-3-642-77582-6_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77584-0

  • Online ISBN: 978-3-642-77582-6

  • eBook Packages: Springer Book Archive

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