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Opioid Analgesics in Clinical Pain Management

  • Chapter
Opioids II

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 104 / 2))

Abstract

Opioid analgesics represent the mainstay of therapy for acute and chronic pain associated with medical illness. Their use in chronic pain management, however, has been controversial, due in part to a dearth of well-controlled studies on their chronic use in clinical pain states and in part to a series of anecdotal and empirical observations made by physicians using these drugs in clinical pain management (Foley 1985). The availability of validated analgesic assay methodologies to assess acute and chronic pain, coupled with the development of sophisticated and sensitive analytical methods to measure opioid drugs in bioftuids, has provided the scientific framework for better definition of the role of the opioid analgesics in man (Foley and Inturrisi 1986).

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Authors
  1. K. M. Foley
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Editors and Affiliations

  1. Abteilung Neuropharmakologie, Max-Planck-Institut für Psychiatrie, Am Klopferspitz 18, W-8033, Martinsried, Germany

    Albert Herz

  2. Mental Health Research Institute, School of Medicine, University of Michigan, 205 Zina Pitcher, 48109, Ann Arbor, MI, USA

    Huda Akil

  3. Medical Center, School of Medicine, New York University, 550 First Avenue, 10016, New York, NY, USA

    Eric J. Simon

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© 1993 Springer-Verlag Berlin Heidelberg

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Foley, K.M. (1993). Opioid Analgesics in Clinical Pain Management. In: Herz, A., Akil, H., Simon, E.J. (eds) Opioids II. Handbook of Experimental Pharmacology, vol 104 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77540-6_29

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  • DOI: https://doi.org/10.1007/978-3-642-77540-6_29

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77542-0

  • Online ISBN: 978-3-642-77540-6

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