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Zusammenfassung

Thrombotische Komplikationen stellen in der operativen Medizin ein erhebliches Problem dar, weil sie häufig auftreten und weil sie eine lebensbedrohliche Lungenembolie verursachen können.

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Literatur

  • Aarburg R von, Gruber UF (1978) Prophylaxe postoperativer thromboembolischer Komplikationen bei hüftgelenksnahen Frakturen. Unfallheilkunde 81:475

    Google Scholar 

  • Arzneimittelkommission der Deutschen Ärzteschaft (1987) Heparin-Dihydergot nicht mehr im Handel. Dtsch Ärzteb 184:1732

    Google Scholar 

  • Becker J, Schampi B (1973) The incidence of postoperative venous thrombosis of the legs. A comparative study on the prophylactic effect of dextran 70 and electrical calf muscle stimulation. Acta Chir Scand 139:357

    PubMed  CAS  Google Scholar 

  • Bergquist D (1979) Prophylaxis of postoperative thromboembolic complications with low-dose heparin. Acta Chir Scand 145:7

    Google Scholar 

  • Bergquist D (1987) Blutungskomplikationen nach niedermolekularem Heparin? Dtsch Med Wochenschr 112:1760

    Google Scholar 

  • Bergquist D, Hallböök T (1980) Prophylaxis of postoperative venous thrombosis in a controlled trial comparing dextran 70 and low-dose heparin. World J Surg 4:239

    Article  Google Scholar 

  • Bergquist D, Efsing HO, Hallböök T, Hedlund T (1979) Thromboembolism after elective and posttraumatic hip surgery. A controlled prophylactic trial with dextran 70 and low-dose heparin. Acta Chir Scand 145:213

    Google Scholar 

  • Biland L (1983a) Die tiefe Venenthrombose. In: Koller F, Duckert F (Hrsg) Thrombose und Embolie. Schattauer, Stuttgart, S 459–467

    Google Scholar 

  • Biland L (1983 b) Venöse Thrombosen. Die oberflächliche Thrombophlebitis. In: Koller F, Dukkert F (Hrsg) Thrombose und Embolie. Schattauer, Stuttgart, S 457–459

    Google Scholar 

  • Bollinger A (1983) Diagnostik: Methoden zum Nachweis von Thrombosen und Embolien. B: Venöse Thrombosen. Ultraschall-Doppler-Methode. In: Koller F, Duckert F (Hrsg) Thrombose und Embolie. Schattauer, Stuttgart, S 143–146

    Google Scholar 

  • Bonnar J, Walsh J (1972) Prevention of thrombosis after pelvic surgery by British dextran 70. Lancet II:614

    Article  Google Scholar 

  • Buttermann G, Theisinger W, Weidenbach A, Hartung R, Welzel D, Pabst HW (1977) Quantitative Bewertung der postoperativen Thromboembolieprophylaxe. Med Klin 72:1624

    PubMed  CAS  Google Scholar 

  • Cameron JS (1984) Coagulation and thromboembolic complications in the nephrotic syndrome. Adv Nephrol 13:75

    CAS  Google Scholar 

  • Cerrato D, Ariano C, Fiacchino F (1978) Deep vein thrombosis and low-dose heparin prophylaxis in neurosurgical patients. J Neurosurg 49:378

    Article  PubMed  CAS  Google Scholar 

  • Collen D, Lijnen HR, Todd PA, Goa KL (1989) Tissue type plasminogen activator–a review of its pharmacology and therapeutic use as thrombocytic agent. Drugs 38:346

    Article  PubMed  CAS  Google Scholar 

  • Davidson AI, Bruni MEA, Matheson NA (1972) A further trial comparing dextran 70 with warfarin in the prophylaxis of postoperative venous thrombosis. Br J Surg 59:314

    Article  PubMed  CAS  Google Scholar 

  • Dexter L (1969) Natural history of pulmonary embolism. In: Sherry S, Brinkhous KM, Genton E, Stengle J (eds) Thrombosis. National Academy of Sciences, Washington, pp 85

    Google Scholar 

  • Dexter L, Dalen JE (1978) Pulmonary embolism and acute cor pulmonale. In: Hurst JW (ed) The heart, 4th edn. McGraw-Hill, New York, pp 1472

    Google Scholar 

  • Duckert F (1983) Antikoagulantien: Heparin. In: Koller F, Duckert F (Hrsg) Thrombose und Embolie. Schattauer, Stuttgart, S 290–305

    Google Scholar 

  • Duckert F, Marbet GA (1983) Therapie: Therapeutische Fibrinolyse. In: Koller F, Duckert F (Hrsg) Thrombose und Embolie. Schattauer, Stuttgart, S 423–449

    Google Scholar 

  • Fareed J, Haas S, Enche H, Wolf H, Wetzel D (1991) Randomisierter Vergleich zwischen niedermolekularem Heparin-Sandoz und unfraktioniertem Heparin.

    Google Scholar 

  • Fitts WT Jr, Erde E, Peskin GW, Front JW (1960) Surgical implications of polycythemia vera. Am Surg 152:548

    Google Scholar 

  • Fridrich R, Müller-Brand J (1983) Diagnostik: Methoden zum Nachweis venöser Thrombosen. Der Radiofibrinogentest. In: Koller F, Duckert F (Hrsg) Thrombose und Embolie. Schattauer, Stuttgart, S 149–153

    Google Scholar 

  • Frimann-Dahl J (1935) Postoperative Röntgenuntersuchungen. Acta Chir Scand [Supp] 36:76

    Google Scholar 

  • Genton E (1983) Medikamentöse Prophylaxe. Plättcheninhibitoren (Plättchenaggregationshemmer). In: Koller F, Duckert F (Hrsg) Thrombose und Embolie, Schattauer, Stuttgart, S 389–390

    Google Scholar 

  • Goldhaber SZ, Kessler CM, Heit J, Markis J, Sharma GVRK, Dawley D, Nagel JS, Meyerovitz M, Kim D, Vaughan DE, Parker JE, Tumeh SS, Drum D, Loscalz J, Reagan K, Selwyn AP, Anderson J, Braunwald E (1988) A randomized trial of recombinant tissue plasminogen activator versus urokinase in the treatment of acute pulmonary embolism. Lancet II (8606):293

    Article  Google Scholar 

  • Goldhaber SZ (1991) Recent advances in the diagnosis and lytic therapy of pulmonary embolism. Chest 99:173

    Article  Google Scholar 

  • Gralnick H, Abrell R (1973) Studies on the procoagulant and fibrinolytic activity of promyelocytes in acute promyelocytic leukemia. Br J Haematol 24:89

    Article  PubMed  CAS  Google Scholar 

  • Gruber UF (1981) Dextran. Biochemische Wirkung, ärztliche Überwachung und Laboratoriumskontrolle. In: Marx R, Thies HA (Hrsg) Kontrolle von Antithrombotika. XXIII. Hamburger Symposium über Blutgerinnung. Editiones Roche, Basel Grenzach, S 255–259

    Google Scholar 

  • Gruber UF (1982) Prevention of fatal postoperative pulmonary embolism by heparin-dihydroergotamine or dextran 70. Br J Surg [Suppl 54] 69:54

    Article  Google Scholar 

  • Gruber UF (1983 a) Prophylaxe. Physikalische Einwirkungen. In: Koller F, Duckert F (Hrsg) Thrombose und Embolie, Schattauer, Stuttgart, S 275–281

    Google Scholar 

  • Gruber UF (1983b) Medikamentöse Prophylaxe. Dextran. In: Koller F, Duckert F (Hrsg) Thrombose und Embolie, Schattauer, Stuttgart, S 355–372

    Google Scholar 

  • Gruber UF, Duckert F, Fridrich R, Torhorst J, Rem J (1977) Prevention of postoperative thromboembolism by dextran 40, low dose of heparin or xantinol-nicotinate. Lancet I:207

    Article  Google Scholar 

  • Gruber UF, Saldeen T, Brokop T et al. (1980) Incidences of fatal postoperative pulmonary embolism after prophylaxis with dextran 70 and low dose heparin: an international multicentre study. Br Med J 280:69

    Article  PubMed  CAS  Google Scholar 

  • Haas S, Haas P, Blümel G (1986) Niedermolekulare Heparine. Eine Übersicht über Wirkungsprofil und bisherige klinische Anwendung. Hämostaseologie 6:180

    CAS  Google Scholar 

  • Haas S, Stemberger A, Fritsche H-M, Wezel D, Wolf H, Lechner F, Blümel G (1987) Prophylaxis of deep vein thrombosis in high risk patients undergoing total hip replacement with low molecular weight heparin plus dihydroergotamine. Arneimittelforschung 37:839

    CAS  Google Scholar 

  • Harris WH, Salzman EW, Athanasoulis C, Waltman AC, Baum S, DeSanctis RW (1974) Comparison of warfarin, low-molecular-weight dextran, aspirin and subcutaneous heparin in prevention of venous thromboembolism following total hip replacement. J Bone Joint Surg 56:1552

    PubMed  CAS  Google Scholar 

  • Hedlund PO (1975) Postoperative venous thrombosis in benign prostatic disease. A study of 316 patients with the 125-fibrinogen test. Scand J Urol Nephrol [Suppl] 27:1

    PubMed  Google Scholar 

  • Heilmann L, Kruch M, Schindler HE (1989) Thromboseprophylaxe in der Gynäkologie: Doppelblind-Vergleich zwischen niedermolekularem (LMWH) und unfraktioniertem (UFH) Heparin. Geburtshilfe und Frauenheilkd: 769–842

    Google Scholar 

  • Heinrich F, Klink K (1984) Lungenembolie. Springer, Berlin Heidelberg New York Tokyo

    Book  Google Scholar 

  • Hirsh JR, Hull D (1978) Comparative value of tests for the diagnosis of venous thrombosis. In: Bernstein EF (ed) Noninvasive diagnostic techniques in vascular disease. Mosby, St. Louis, pp 382

    Google Scholar 

  • Hirsh J, Ofosu FA, Levine M (1987) The development of low molecular weight heparins for clinical use. In: Verstraete M (ed) Thrombosis and haemostasis. University Press, Leuven, pp 325

    Google Scholar 

  • Hohl M, Lüscher KP, Gruber UF (1978) Nebenwirkungen bei perioperativer Thromboembolieprophylaxe. Gynäkologe 11:45

    Google Scholar 

  • Hohl MK (1983) Prophylaxe der tiefen Beinvenenthrombosen und Lungenembolien in der Gynäkologie. In: Koller F, Duckert F (Hrsg) Thrombose und Embolie, Schattauer, Stuttgart, S 506–509

    Google Scholar 

  • Inman WHW, Vessey MP (1968) Investigation of deaths from pulmonary, coronary and cerebral thrombosis and embolism in women of childbearing age. Br Med J II:193

    Article  Google Scholar 

  • Jackman FR, Perry BJ, Siddons H (1978) Deep vein thrombosis after thoracotomy. Thorax 33:61

    Google Scholar 

  • Joffe SN (1975) Incidence of postoperative deep vein thrombosis in neurosurgical patients. J Neurosurg 42:201

    Article  PubMed  CAS  Google Scholar 

  • Jordan WM (1961) Pulmonary embolism. Lancet 11:1146

    Article  Google Scholar 

  • Jung W, Fridrich F, Duckert F, Gruber F (1975) Der Radiofibrinogentest zur Diagnose frischer tiefer Venenthrombosen. Schweiz Med Wochenschr 105:391

    PubMed  CAS  Google Scholar 

  • Kakkar VV (1978) The current status of low dose heparin in the prophylaxis of thrombophlebitis and pulmonary embolism. World J Surg 2:3

    Article  PubMed  CAS  Google Scholar 

  • Kakkar VV, Howe CT, Nicolaides AN, Remey JTG, Clarke MB (1970) Deep vein thrombosis of the leg: is there a high risk group? Am J Surg 120:527

    Article  PubMed  CAS  Google Scholar 

  • Kappert A (1976) Lehrbuch und Atlas der Angiologie. Huber, Bern, S 242–245

    Google Scholar 

  • Kirchmaier CM (1983) Antithrombin III in patients with proteinuria. In: Wenzel E, Nienhaus K, Rosenberg RD (eds) Antithrombin III – Biochemistry, function, assay and clinical significance. Ann Univ Sarav Med [Suppl] 3:151

    Google Scholar 

  • Koller F (1983) Prädisposition zu venösen Thrombosen und Lungenembolien. In: Koller F, Duckert F (Hrsg) Thrombose und Embolie, Schattauer, Stuttgart, S 51–83

    Google Scholar 

  • Koppenhagen K (1991) Klinische Studien zur Thromboseprophylaxe. Unfallchirurgie 17, Sonderheft 1:8–11

    Google Scholar 

  • Ludwig H (1983) Venenthrombosen in der Schwangerschaft und im Wochenbett. In: Koller F, Duckert F (Hrsg) Thrombose und Embolie, Schattauer, Stuttgart, S 482–501

    Google Scholar 

  • Mammen EF (1982) Oral contraceptives and blood: a critical review. Am J Obstet Gynecol 142:781

    PubMed  CAS  Google Scholar 

  • Mammen EF (1987) Gerinnungsstörungen: Eine Herausforderung für den Kliniker. In: Mammen EF (Hrsg) Intensivrnedizin aktuell. Sicherheit in Diagnose und Therapie von Gerinnungsstörungen. Medizinische Verlagsgesellschaft, Marburg

    Google Scholar 

  • Marbert GA (1983) Prädisposition zur Thrombose aufgrund von Laboratoriumsbefunden. In: Koller F, Duckert F (Hrsg) Thrombose und Embolie, Schattauer, Stuttgart, S 85–98

    Google Scholar 

  • May R (1981) Physikalische Methoden der Thromboseprophylaxe. In: Vinazzer H (Hrsg) Thrombose und Embolie. Springer, Berlin Heidelberg New York, S 213–220

    Google Scholar 

  • Mayo ME, Halil T, Browse NL (1971) The incidence of deep vein thrombosis after prostatectomy. Br J Urol 43:738

    Article  PubMed  CAS  Google Scholar 

  • McCarthy ST, McQueen J, Johnstone FD et al. (1974) A comparison oflow dose subcutaneous heparin and intravenous dextran 70 in the prophylaxis of deep venous thrombosis after gynaecological surgery. J Obstet Gynaecol Br Commonw 81:486

    Article  PubMed  CAS  Google Scholar 

  • McCarthy ST, Tanner JJ, Robertson D et al. (1977) Low dose heparin as a prophylaxis against deep vein thrombosis after acute stroke. Lancet II:800

    Article  Google Scholar 

  • McKenzie PJ, Loach AB (1986) Local anaesthesia for orthopaedic surgery. Br J Anaesth 58:779

    Article  PubMed  CAS  Google Scholar 

  • Modig J, Kalstrom G, Maripun E, Sahlstedt B (1980) Thromboembolism after total hip replacement: role of epidural and general anesthesia. Anesth Analg 62:174

    Google Scholar 

  • Modig J, Borg T, Bagge L, Saldeen T (1983) Role of extradural and of general anesthesia in fibrinolysis and coagulation after total hip replacement. Br J Anaesth 55:625

    Article  PubMed  CAS  Google Scholar 

  • Nicolaides AN, Field ES, Kakkar VV, Yates-Bell AJ, Taylor S, Clarke MB (1972) Prostatectomy and deep vein thrombosis. Br J Surg 59:487

    Article  PubMed  CAS  Google Scholar 

  • Partsch H (1978) Doppler-Ultraschall und Isotopen-Phlebographie zur praktischen Diagnostik von venösen Beckenabflußhindernissen. In: Kriessmann A, Bollinger A (Hrsg) UltraschallDoppler- Diagnostik. Thieme, Stuttgart, S 161–166

    Google Scholar 

  • Pearson TC, Wetherley-Mein G (1978) Vascular occlusive episodes and venous haematocrit in primary proliferative polycythaemia. Lancet II:1219

    Article  Google Scholar 

  • Pezzuoli G, Neri Seneri GG, Coggi G et al. (1987) Step-multicenter double-blind controlled clinical trial on the prevention of fatal pulmonary embolism with the low molecular weight heparin Cy 216 (Abstr.). In: Breddin K (ed) Fraxiparine. Analytical and structural data, pharmacology, clinical trials. Schattauer, Stuttgart New York, pp 12

    Google Scholar 

  • Pineo GF, Brian MC, Gallus AS et al. (1974) Tumors, mucus production and hypercoagulability. Ann NY Acad Sci 230:262

    Article  PubMed  CAS  Google Scholar 

  • Roessle R (1937) tiber die Bedeutung und Entstehung der Wadenvenenthrombosen. Virchows Arch 300:180

    Article  Google Scholar 

  • Sagar S, Stamatakis JD, Higgins AF, Nair D, Maffei FH, Thomas DP, Kakkar VV (1976a) Efficacy of low-dose heparin in prevention of extensive deep-vein thrombosis in patients undergoing total hip replacement. Lancet I:1151

    Article  Google Scholar 

  • Sagar S, Stamatakis JD, Thomas DP, Kakkar VV (1976b) Oral contraceptives, antithrombinIII- activity and postoperative deep-vein thrombosis. Lancet 1:509

    Article  PubMed  CAS  Google Scholar 

  • Sasahara AA, Koppenhagen K, Häring R, Welzel D, Wolf H (1986) Low molecular weight heparin plus dihydroergotamine for prophylaxis of postoperative deep vein thrombosis. Br J Surg 73:697

    Article  PubMed  CAS  Google Scholar 

  • Schaub N, Duckert F, Friedrich R, Gruber UF (1975) Häufigkeit postoperativer tiefer Venenthrombosen bei Patienten der Allgemeinen Chirurgie und Urologie. Langenbeck’s Arch Chir 340:23

    Article  CAS  Google Scholar 

  • Schöndorf TH, Weber U (1980) Prevention of deep vein thrombosis in orthopedic surgery with the combination oflow dose heparin plus either dihydroergotamine or dextran. Scand J Haematol [Suppl 36] 25:126

    Google Scholar 

  • Schrader J, Köstering H, Kramer P, Scheler F (1982) Antithrombin III – Substitution bei dialysepflichtiger Niereninsuffizienz. Dtsch Med Wochenschr 107:1847

    Article  PubMed  CAS  Google Scholar 

  • Schramm W (1984) Thromboembolie – Die klinische Bedeutung des Antithrombin III. Internist (Berlin) 28:88

    Google Scholar 

  • Seglias J, Gruber UF (1979) Dosage in low-dose heparin prophylaxis. Haemostasis 8:361

    PubMed  CAS  Google Scholar 

  • Sevitt S (1962) Venous thrombosis and pulmonary embolism. Their prevention by oral anticoagulants. Am J Med 33:703

    Article  PubMed  CAS  Google Scholar 

  • Sevitt S (1969) Venous thrombosis in injured patients. In: Sherry S, Brinkhous KM, Genton E, Stengle JM (eds) Thrombosis. National Academiy of Sciences, Washington

    Google Scholar 

  • Sevitt S, Gallagher NG (1959) Prevention of venous thrombosis and pulmonary embolism in injured patients. Lancet II:981

    Article  Google Scholar 

  • Sise HS, Booth J, O’Leary R, O’Riordan C, Banks H (1972) Double blind evaluation of dextran 40 for prevention of venous thrombosis in hip fracture using 125-I-fibrinogen test. Circulation 46:222

    Google Scholar 

  • Thaler E, Lechner K (1981) Antithrombin III deficiency and thromboembolism. Clin Haematol 10:369

    PubMed  CAS  Google Scholar 

  • Thies HA, Oppelt W (1961) Zur Strömungsgeschwindigkeit des Blutes vor und nach Operationen. Chirurg 32:135

    PubMed  CAS  Google Scholar 

  • Thorburn J, Louden JR, Vallance R (1980) Spinal and general anesthesia in total hip replacement: frequency of deep vein thrombosis. Br J Anaesth 52:1117

    Article  PubMed  CAS  Google Scholar 

  • Tilsner V (1985) Antithrombin III. Bedeutung, Diagnostik und Therapie. Med Welt 36:534

    Google Scholar 

  • Vinazzer H (1981) Klinische Diagnostik venöser Thrombosen und ihre Wertigkeit. In: Vinazzer H (Hrsg) Thrombose und Embolie. Springer, Berlin Heidelberg New York, S 78–81

    Google Scholar 

  • Voigt J, Hamelmann H, Hedderich J, Seifert J, Buchhammer T, Köhler A (1986) Wirksamkeit und unerwünschte Wirkungen von niedermolekularem Heparin-Dihydergotamin zur Thromboembolieprophylaxe in der Abdominalchirurgie. Zentralbl Chir 111:1286

    Google Scholar 

  • Weber W, Nagel G (1976) Blutgerinnungsstörungen als paraneoplastisches Syndrom. In: Neuhaus K, Duckert F (Hrsg) Blutgerinnung und Antikoagulation. Schattauer, Stuttgart, S 41–48

    Google Scholar 

  • Werthemann A, Rutishauser G (1954) Zur pathologischen Anatomie der Thrombose. In: Koller T, Merz WR (Hrsg) Thrombose und Embolie. Schwabe, Basel, S 527–542

    Google Scholar 

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Lorentz, A. (1992). Thrombose. In: List, W.F., Osswald, P.M. (eds) Intensivmedizinische Praxis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77498-0_21

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