Prevalence of Antibody to Helicobacter pylori in Children in Northern Nigeria

  • C. Holcombe
  • S. Tsimiri
  • D. M. Jones
  • J. Eldridge
Conference paper


Helicobacter pylori infection is uncommon in children in the West [1], but it is important to remember that H. pylori infection has a worldwide distribution. The social, cultural and environmental influences on populations in the developing world are very different and have a profound effect on the infection profile.


Pylorus Infection Adequate Facility Antibiotic Intake Infection Profile Gastric Mucosal Biopsy 
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  1. 1.
    Jones DM, Eldridge J, Fox AJ, Sethi P, Whorwell PJ (1986) Antibody to the gastric Campylobacter-like organism (‘Campylobacter pyloridis’) — clinical correlations and distribution in the normal population. J Med Microbiol 22:57–62PubMedCrossRefGoogle Scholar
  2. 2.
    Holcombe C, Omotara BA, Eldridge J, Jones DM (1992) The commonest bacterial infection in Africa. Helicobacter pylori: A random serological survey. Am J Gastroenterology 87 (1): 28–30Google Scholar
  3. 3.
    Holcombe C, Kaluba J, Lucas SB (1991) Non-ulcer dyspepsia in Nigeria: a case control study. Trans R Soc Trop Med Hyg 4:553–555CrossRefGoogle Scholar
  4. 4.
    Megraud F, Brassens-Rabbe MP, Denis F, Belbouri A, Hoa DQ (1989) Seroepidemiology of Campylobacter pylori in various populations. J Clin Microbiol 27 (8) 1870–1873PubMedGoogle Scholar
  5. 5.
    Rouvroy D, Bogaerts J, Nsengiumwa O, Omar M (1987) Campylobacter pylori, gastritis and peptic ulcer disease in central Africa. Br Med J 295:1174CrossRefGoogle Scholar
  6. 6.
    Weir WRC, Goodgame R, Kiire CF, Lucas SB (1988) Campylobacter like organisms and gastritis in Africa. Trans R Soc Trop Med Hyg 82:172PubMedCrossRefGoogle Scholar
  7. 7.
    Mitchell HM, Lee A, Bohane TD (1989) Evidence for person to person spread of Campylobacter pylori. In: Rathbone BJ, Heatley RV (eds) Campylobacter pylori and gastroduodenal disease. Blackwell, London, pp 197–202Google Scholar
  8. 8.
    Holcombe C, Lucas SB, Umar H, Abba A (1990) Helicobacter pylori ( = Campylobacter) in Africa. Trans R Soc Trop Med Hyg 84 (2): 294–296PubMedCrossRefGoogle Scholar
  9. 9.
    Holcombe C, Lucas SB, Thorn C (1990) Helicobacter pylori and Non-ulcer dyspepsia in Northern Nigeria. Rev Rsp Enferm Dig 78 (1):71Google Scholar
  10. 10.
    Holcombe C, Thorn C, Kaluba J, Lucas SB (1991) Helicobacter pylori clearance in the treatment of non-ulcer dyspepsia. Alimentary Pharmacology & Therapeutics 6 (1): 119CrossRefGoogle Scholar
  11. 11.
    Collins R, Patchett S, Keane C, O’Norain C (1991) Reinfection with Helicobacter pylori due to intrafamilial clustering of the organism. Rev Esp Enferm Dig 78 (1): 9Google Scholar
  12. 12.
    Tovey FI, Tunstall M (1975) Duodenal ulcer in black populations in Africa south of the Sahara. Gut 16:564–576PubMedCrossRefGoogle Scholar
  13. 13.
    Holcombe C, Babayo U (1991) The pattern of malignant disease in North East Nigeria. Trop Geogr Med 43 (2): 189–192PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • C. Holcombe
    • 1
  • S. Tsimiri
    • 1
  • D. M. Jones
    • 1
  • J. Eldridge
    • 2
  1. 1.Academic Department of SurgeryUniversity of MaiduguriNorthern Nigeria
  2. 2.Public Health LaboratoryManchesterUK

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