Skip to main content
SpringerLink
Log in

Increased Incidence of Helicobacter pylori in Gastric Cancer, as Shown by the Rapid Urease Test

  • Conference paper
Helicobacter pylori and Gastroduodenal Pathology

  • 99 Accesses

Abstract

Nowadays it is widely accepted that Helicobacter pylori infection is the main etiologic factor in chronic gastritis type B (CGB). However, its contribution to the developement of gastric ulcer remains controversial. In vivo studies on gnotobiotic piglets [1,2] and healthy humans [3, 4] have shown that a typical CGB picture can be reproduced by the ingestion of this microorganism. A further point supporting a relationship between H. pylori and CGB is the possibility of inducing a partial or complete histologic recovery of the disease after the clearance of bacteria by bismuth salts or antibiotics [5–8].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Krakowka S, Morgan DR, Kraft WG, Leunk RD (1987) Establishment of gastric Campylobacter pylori infection in the neonatal gnotobiotic piglet. Infect Immun 55:2789–2796

    PubMed  CAS  Google Scholar 

  2. Lambert JR, Borromeo M, Pinkard KJ, Turner H, Chapman CB, Smith ML (1987) Colonization of gnotobiotic piglets with Campylobacter pyloridis, an animal model? J Infect Dis 155:1344

    Article  PubMed  CAS  Google Scholar 

  3. Marshall BJ, Armstrong JA, McGechie DB, Glancy RJ (1985) Attempts to fulfill Koch’s postulates for pyloric Campylobacter. Med J Aust 142:436–439

    PubMed  CAS  Google Scholar 

  4. Morris A, Nicholson G (1987) Ingestion of Campylobacter pyloridis causes gastritis and raised fasting gastric pH. Am J Gastroenterol 82:192–199

    PubMed  CAS  Google Scholar 

  5. McNulty CAM, Gearty JC, Crump B, Davis M, Donovan IA, Melikian V, Lister DM, Wise R (1986) Campylobacter pyloridis and associated gastritis: investigator blind, placebo controlled trial of bismuth salicylate and erythromycin ethylsuccinate. Br Med J 293:645–649

    Article  CAS  Google Scholar 

  6. Rauws EAJ, Langenberg W, Houthoff HJ, Zanen HC, Tytgat GNJ (1988) Campylobacter pyloridis associated chronic active antral gastritis. A prospective study. Gastroenterology 94:33–40

    PubMed  CAS  Google Scholar 

  7. Morgan D, Kraft W, Bender M, Pearson A (1988) Nitrofurans in the treatment of gastritis associated with Campylobacter pyloridis, Gastroenterology 95:1178–1184

    PubMed  CAS  Google Scholar 

  8. Glupczynski Y, Burette A, Labbe M, Deprez C, De Reuck M, Deltenre M (1988) Campylobacter pylori associated gastritis. A double-blind placebo-controlled trial with Amoxycillin. Am J Gastroenterol 83:365–372

    PubMed  CAS  Google Scholar 

  9. Lopez-Abente G, Escolar A, Errezola M (1984) Atlas del cancer en España. Departamento de Sanidad del Gobierno Vasco, Vitoria, pp 37–44

    Google Scholar 

  10. Arvind AS, Cook RS, Tabaqchali S, Farthing MJG (1988) One minute endoscopy room test for Campylobacter pylori. Lancet 1:704

    Article  PubMed  CAS  Google Scholar 

  11. Boixeda D, San Roman AL, Canton R, Erdozain JC, Redondo C, Moreira VF, De Rafael L (1990) Is rapid urease test sufficient for the diagnosis of Helicobacter pylori in an endoscopy unit? Rev Esp Enferm Dig 78 [Suppl 1]:15

    Google Scholar 

  12. Jiang SJ, Liu WZ, Zhang DZ (1987) Campylobacter-like organisms in chronic gastritis, peptic ulcer and gastric carcinoma. Scand J Gastroenterol 22:553–558

    Article  PubMed  CAS  Google Scholar 

  13. Feng YY, Wang Y (1988) Campylobacter pylori in patients with gastritis, peptic ulcer and carcinoma of the stomach in Lanzhou, China. Lancet 1:1055–1056

    Article  PubMed  CAS  Google Scholar 

  14. Inouye H, Tonokatsu Y, Mikami J, Yamamoto I, Fukuda Y, Tamura K, Shimoyama T, Yamamoto Y, Tanaka T, Tamura T, Shoji K, Ishii E, Kishi T (1988) Campylobacter pylori in patients with gastric disease in Japan. I Workshop “Gastroduodenal pathology and Campylobacter pylori”, Bordeaux, p 129

    Google Scholar 

  15. Jaskiewcz K, Louwrens HD, Woodroof CW, Van Wyk MJ, Price SK (1989) The association of Campylobacter pylori with mucosal pathological changes in aq population at risk for gastric cancer. S Afr Med J 75:417–419

    Google Scholar 

  16. Pauli G, Yardley JH (1989) Pathology of Campylobacter pylori-associated gastric and esophageal lesions. In: Blaser MJ (ed.) Campylobacter pylori in gastritis and peptic ulcer disease. IgakuShoin, New York, pp 73–97

    Google Scholar 

  17. Scott N, Lansdown M, Rathbone B, Murday L, Wyatt JI, McMahon M, Dixon MF, Quirke P (1990) Helicobacter gastritis and intestinal metaplasia in a gastric cancer family. Lancet 335:728

    Article  PubMed  CAS  Google Scholar 

  18. Fox JG, Correa P, Taylor NS, Zavala D, Fontham E, Janney F, Rodriguez E, Hunter F, Diavolitsis S (1989) Campylobacter pylori associated gastritis and immune response in a population at increased risk of gastric carcinoma. Gastroenterology 84:775–781

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Gastroenterology, Hospital “Ramon y Cajal,” Alcala de Henares University, Madrid, Spain

    D. Boixeda, A. L. San Roman, C. Martin de Argila & L. A. Gil Grande

  2. Department of Microbiology, Hospital “Ramon y Cajal,” Alcala de Henares University, Madrid, Spain

    R. Cantón & L. de Rafael

  3. Department of Pathology, Hospital “Ramon y Cajal,” Alcala de Henares University, Madrid, Spain

    C. Redondo

Authors
  1. D. Boixeda
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. L. San Roman
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. C. Martin de Argila
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. Cantón
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. C. Redondo
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. L. A. Gil Grande
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. L. de Rafael
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Hospital de la Princesa, Autonoma University of Madrid, Diego de Leon, 62, 28006, Madrid, Spain

    José M. Pajares M.D., Ph.D. (Professor of Medicine, Head of Department of Gastroenterology) (Professor of Medicine, Head of Department of Gastroenterology)

  2. Free University of Amsterdam, De Boelelaam 1117, 1081 HV, Amsterdam, The Netherlands

    A. Salvador Peña M.D., Ph.D. (Professor of Gastrointestinal Immunology) (Professor of Gastrointestinal Immunology)

  3. Abt. Innere Medizin II, Universitäts Klinik Ulm, Robert-Koch-Str. 8, W-7900, Ulm, Germany

    Peter Malfertheiner Prof. Dr. med.

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Boixeda, D. et al. (1993). Increased Incidence of Helicobacter pylori in Gastric Cancer, as Shown by the Rapid Urease Test. In: Pajares, J.M., Peña, A.S., Malfertheiner, P. (eds) Helicobacter pylori and Gastroduodenal Pathology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77486-7_39

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-77486-7_39

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77488-1

  • Online ISBN: 978-3-642-77486-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation