A Role for Helicobacter pylori in Gastric Carcinoma?
The exact aetiology of gastric carcinoma is unknown. Many impetuses are known or suspected to play a role in the pathogenesis of gastric cancer. It is generally accepted in the literature that induction of gastritis is the initial event in the pathogenesis. If the inflammation persists for many years, this will eventually lead to the development of intestinal metaplasia and atrophia. Together with other impetuses, such as, for instance, toxic substances, this can finally lead to the development of gastric cancer. Of course this sequence is much more complicated and not unraveled to its full extent.
KeywordsGastritis Noma Dyspepsia Haematoxylin
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