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A Role for Helicobacter pylori in Gastric Carcinoma?

  • R. J. L. F. Loffeld
  • I. Willems
  • J. W. Arends
Conference paper

Abstract

The exact aetiology of gastric carcinoma is unknown. Many impetuses are known or suspected to play a role in the pathogenesis of gastric cancer. It is generally accepted in the literature that induction of gastritis is the initial event in the pathogenesis. If the inflammation persists for many years, this will eventually lead to the development of intestinal metaplasia and atrophia. Together with other impetuses, such as, for instance, toxic substances, this can finally lead to the development of gastric cancer. Of course this sequence is much more complicated and not unraveled to its full extent.

Keywords

Gastric Cancer Gastric Carcinoma Intestinal Metaplasia Bacterial Load Healthy Blood Donor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • R. J. L. F. Loffeld
    • 1
  • I. Willems
    • 2
  • J. W. Arends
    • 2
  1. 1.Department of Internal MedicineUniversity Hospital MaastrichtMaastrichtThe Netherlands
  2. 2.Department of PathologyUniversity Hospital MaastrichtMaastrichtThe Netherlands

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