Abstract
Several histological and microbiological detection methods are available for the diagnosis of Helicobacter pylori-associated gastritis. However, these require endoscopy with biopsies from the gastric antrum. Therefore they are not feasible for epidemiological studies. To facilitate the diagnosis, non-invasive techniques such as breath tests and serological detection of H. pylori antibodies have been developed [1–4]. Home-made serological tests with different antigen preparations are widely employed. Several commercial enzyme-linked immuno sorbent assays (ELISA) have recently become available. A high diagnostic yield, and high sensitivity and specificity values are claimed for these tests. In the present study one such test, the Bio-Rad GAP test, was compared with a homemade ELISA used in our laboratory.
This paper is published in extended form entitled “Usefulness of a new serological test (Bio-Rad) to diagnose Helicobacter pylori associated gastritis” in the Journal of Clinical Microbiology (1991) 29: 283–286.
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References
Loffeld RJLF, Stobberingh E, Flendrig JA, van Spreeuwel JP, Arends JW (1989) Diagnostic value of an immunoassay to detect anti-Campylobacter pylori antibodies in non-ulcer dyspepsia. Lancet i : 1182–1185
Hirschl AM, Pletschetter M, Hirschl MH, Berger J, Stanck G, Rotter ML (1988) Comparison of different antigen preparations i an evaluatio of the immune response to Campylobacter pylori. Eur J Clin Microbiol Infect Dis 7:570–575
Perez-Perez GI, Dworkin BM, Chodes JE, Blaser MJ (1988) Campylobacter antibodies in humans. Ann Intern Med 109:11–17
Wyatt JI, Rathbone BJ (1989) The role of serology in the diagnosis of Campylobacter pylori infection. Scand J Gastroenterology 24:27–34
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© 1993 Springer-Verlag Berlin Heidelberg
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Loffeld, R.J.L.F., van den Oever, H.L.A., Stobberingh, E. (1993). Usefulness of Two Enzyme-Linked Immunosorbent Assay Systems for the Diagnosis of Helicobacter pylori-Associated Gastritis. In: Pajares, J.M., Peña, A.S., Malfertheiner, P. (eds) Helicobacter pylori and Gastroduodenal Pathology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77486-7_34
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DOI: https://doi.org/10.1007/978-3-642-77486-7_34
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