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Antibodies to Vacuolating Toxin of Helicobacter pylori in Dyspeptic Patients

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Helicobacter pylori and Gastroduodenal Pathology

Abstract

Certain Helicobacter pylori (HP) strains are capable of inducing a cytopathic effect in mammalian cells in vitro consisting in the formation of intracytoplasmic vacuoles [1, 2]. In vitro cells exposed to broth culture filtrate (BCF) of vacuolating HP (VHP) strains die more rapidly than do cells exposed to BCF of non-VHP ones and to uninoculated broth. In addition, VHP causes a strong reduction of the proliferation index of Epstein-Bass Virus (EBV) -transformed B lymphocytes [2].

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© 1993 Springer-Verlag Berlin Heidelberg

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Figura, N. et al. (1993). Antibodies to Vacuolating Toxin of Helicobacter pylori in Dyspeptic Patients. In: Pajares, J.M., Peña, A.S., Malfertheiner, P. (eds) Helicobacter pylori and Gastroduodenal Pathology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77486-7_31

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  • DOI: https://doi.org/10.1007/978-3-642-77486-7_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77488-1

  • Online ISBN: 978-3-642-77486-7

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