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Local and Systemic Antibody Responses During Helicobacter pylori Infections

  • A. R. Stacey
  • P. R. Hawtin
  • D. G. Newell
Conference paper

Abstract

The majority of patients with a Helicobacter pylori infection mount a systemic antibody response which is easily detectable by serological assays such as the enzyme-linked immunosorbent assay (ELISA) [1]. Positive results in bacterial agglutination and complement fixation tests [2] suggest that these antibodies possess some anti-bacterial activity. However, the infection persists suggesting an underlying ineffectiveness in the ability of the systemic antibody response to eradicate the infection.

Keywords

Pylorus Infection Normal Human Serum Complement Fixation Test Gastric Mucosal Biopsy Liquid Chromatography Fraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Newell DG, Rathbone BJ (1989) The serodiagnosis of Campylobacter pylori infection—a review. Serodiagn Immunother 3:1–6CrossRefGoogle Scholar
  2. 2.
    Jones DM, Lessels AM, Eldridge J (1984) Campylobacter-like organisms on the gastric mucosa: culture, histology and serological studies. J Clin Pathol 37:1002–1006PubMedCrossRefGoogle Scholar
  3. 3.
    Stacey AR, Hawtin PR, Newell DG (1990) Local immune responses to Helicobacter pylori infections. In: Malfertheiner P, Ditschuneit H (eds) Helicobacter pylori, gastritis and peptic ulcer. Springer, Berlin Heidelberg New York, pp 162–166Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • A. R. Stacey
    • 1
  • P. R. Hawtin
    • 1
  • D. G. Newell
    • 1
  1. 1.PHLS Centre for Applied Microbiology and ResearchSalisburyUK

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