Oxygen Transport in the Early Embryo

  • R. Baumann
Conference paper


This chapter provides a short review of oxygen transport conditions during the early embryonic development of the chick. Since mammalian embryos cannot be investigated in situ during the period of organogenesis, the experimental model of choice is the avian embryo. While there are differences in the boundary conditions for oxygen uptake between early mammalian and avian embryos, they share functional constraints which may have contributed to the persistence of the specific embryonic hemoglobins. Red blood cells and the circulatory system are the first structures that differentiate in the vertebrate embryo. The yolk sac is the site of embryonic erythropoiesis in higher vertebrates. It produces the first population of red cells (primitive erythrocytes), which synthesize the specific embryonic hemoglobins. These hemoglobins are subsequently replaced by either adult or fetal hemoglobin.


Chick Embryo Oxygen Transport Early Embryo Dorsal Aorta Oxygen Binding 
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  1. Baumann FH, Baumann R (1977) A comparative study of the respiratory properties of bird blood. Respir Physiol 31: 333–343PubMedCrossRefGoogle Scholar
  2. Baumann R, Gros G (1984) A comparativ study of the aggregation of avian embryonic and adult hemoglobin. In: Schnek AG, Paul C (eds) Hemoglobin. Editions de l’université de Bruxelles, pp 151–160Google Scholar
  3. Baumann R, Padeken S, Haller EA (1982) Functional properties of embryonic chicken hemoglobins. J Appl Physiol 53: 1439–1448PubMedGoogle Scholar
  4. Baumann R, Padeken S, Haller EA, Brilmayer T (1983) Effects of hypoxia on oxygen affinity, hemoglobin pattern and blood volume of early chicken embryos. Am J Physiol 244: R733–R741PubMedGoogle Scholar
  5. Brittain T, Wells RMG (1983) Oxygen transport in early mammalian development:molecular physiology of embryonic hemoglobins. In: Johnson MH (ed) Development in mammals, vol 5. Elsevier, Amsterdam, pp 136–154Google Scholar
  6. Bruns GAP, Ingram VM (1973) The erythroid cells and hemoglobins of the chick embryo. Philos Trans R Soc London [Biol] 266: 225–305CrossRefGoogle Scholar
  7. Czelusniak J, Goodmann M, Hewett-Emmett D, Weiss ML, Venta PJ, Tashian RE (1982) Phylogenetic origins and adaptive evolution of avian and mamalian hemoglobin genes. Nature 298: 297–300PubMedCrossRefGoogle Scholar
  8. Engel JD, Rusling DJ, McCune KC, Dodgson JB (1983) Unusual structure of the chicken embryonic alpha-globin gene. Proc Natl Acad Sci USA 80: 1392–1396PubMedCrossRefGoogle Scholar
  9. Girard H (1973) Arterial pressure in the chick embryo. Am J Physiol 224: 454–460PubMedGoogle Scholar
  10. Grima M, Girard H, Dejours P (1983) Blood oxygen consumption and erythrocyte types in embryonic and postnatal chicken. Am J Physiol 244: C32–C36PubMedGoogle Scholar
  11. Holland RAB, Rimes AF, Comis A, Tyndale-Biscoe CH (1989) Oxygen carriage and carbonic anhydrase activity in the blood of a marsupial, the tammar wallaby (Macropus eugenii), during early development. Respir Physiol 73: 69–86CrossRefGoogle Scholar
  12. Lapennas GN, Reeves RB (1983) Oxygen equilibrium curve shape in blood of chicken embryos. Respir Physiol 52: 13–26PubMedCrossRefGoogle Scholar
  13. Lomholt JP (1984) A preliminary study of local oxygen tensions inside birds eggs and gas exchange during early stages of embryonic development. In: Seymour RS (ed) Respiration and metabolism of embryonic vertebrates. Junk, Dordrecht, pp 289–297CrossRefGoogle Scholar
  14. Meuer HJ, Baumann R (1988) Oxygen pressure in intra- and extraembryonic blood vessels of early chick embryo. Respir Physiol 71: 331–332PubMedCrossRefGoogle Scholar
  15. Meuer HJ, Sieger U, Baumann R (1989) Measurement of pH in blood vessels and interstitium of 4 and 6 day old chick embryos. J Dev Physiol 11: 354–359PubMedGoogle Scholar
  16. Romanoff AL (1960) The avian embryo. Macmillan, New YorkGoogle Scholar
  17. Romanoff AL (1972) Pathogenesis of the avian embryo. Wiley, New YorkGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 1992

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  • R. Baumann

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