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Polytene Chromosomes in Mutagenesis

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Advances in Mutagenesis Research

Part of the book series: Advances in Mutagenesis Research ((MUTAGENESIS,volume 4))

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Abstract

Since Muller introduced mutagenesis research in Drosophilain the early 1920s and reported the production of mutations by X-rays in 1927, Drosophilahas become one of the so far genetically best-analyzed eukaryotes. This is based on nearly a century of work in generating and analyzing mutants. Not only the ease of handling Drosophila melanogaster, the high reproductivity, the short generation time, and the existence of only four chromosomes per haploid genome have made the fly so suitable for genetic investigation, but also the existence of the giant polytene chromosomes in salivary gland nuclei played a crucial role in analyzing mutations.

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  1. Institut für Genetik, der Freien Universität Berlin, Arnimallee 7, 1000, Berlin 33, Germany

    A. Hofmann & G. Korge

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  1. FB9 der Universität Gesamthochschule Essen, Universitätsstraße 5, Postfach 10 37 64, 4300, Essen 1, Germany

    Günter Obe

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Hofmann, A., Korge, G. (1993). Polytene Chromosomes in Mutagenesis. In: Obe, G. (eds) Advances in Mutagenesis Research. Advances in Mutagenesis Research, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77466-9_7

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