Opioids pp 37-52 | Cite as

Characterization of Opioid-Binding Proteins and Other Molecules Related to Opioid Function

  • A. P. Smith
  • H. H. Loh
  • N. M. Lee
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 104 / 1)

Abstract

Nearly 2 decades after their discovery in mammalian brain, opioid receptors remain largely uncharacterized structurally and functionally. While a great body of pharmacological and biochemical information has accumulated from studies of membrane-bound opioid receptors, continued difficulties in purifying these receptors has precluded investigators from obtaining such standard knowledge as the receptor’s amino acid sequence, its overall conformation in the cell membrane, the location of its ligand-binding site, and the identity of functional molecules associated with it.

Keywords

Dopamine Tyrosine Influenza Cysteine Morphine 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • A. P. Smith
  • H. H. Loh
  • N. M. Lee

There are no affiliations available

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