Skip to main content

Conservative Management of Chronic Pancreatitis

  • Conference paper
Standards in Pancreatic Surgery

Abstract

Pain and the symptoms of malabsorption are the cardinal manifestations of chronic pancreatitis that require treatment. Complications such as bile duct obstruction secondary to fibrosis or intrapancreatic retention cysts and pseudocysts may also arise and require treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 119.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 159.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. DiMagno EP, Ciain JE (1986) Chronic pancreatitis. In: Go VLW, Gardner JD, Brooks FP, Lebenthal E, DiMagno EP, Scheele GA (eds) The exocrine pancreas: biology, pathobiology and diseases. Raven, New York, pp 541–575

    Google Scholar 

  2. Ammann RW, Buehler H, Muench R, Freiburghaus AW, Siegenthaler W (1987) Differences in the natural history of idiopathic (nonalcoholic) and alcoholic chronic pancreatitis. A comparative long-term study of 287 patients. Pancreas 2:368–377

    Article  PubMed  CAS  Google Scholar 

  3. Layer P, Kalthoff L, Ciain JE, DiMagno EP (1985) Nonalcoholic chronic pancreatitis — two diseases? Dig Dis Sci 30:980

    Google Scholar 

  4. Owyang C (1989) Control of exocrine pancreatic secretion. Regul Pept 1:1–7

    Google Scholar 

  5. Rowell WG, Toskes PP (1989) Pain in chronic pancreatitis. In: Barkin J, Rogers A (eds) Difficult decisions in digestive diseases. Yearbook Medical, Chicago, pp 192–197

    Google Scholar 

  6. Boivin M, Lanspa SJ, Zinsmeister AR, Go VLW, DiMagno EP (1990) Are diets associated with different rates of human interdigestive and postprandial pancreatic enzyme secretion? Gastroenterology 99:1763–1771

    PubMed  CAS  Google Scholar 

  7. Pap A, Nauss LA, DiMagno EP (1990) Is percutaneous celiac plexus block (PCPB) associated with pain relief in chronic pancreatitis? A comparison among analgesic, alcohol and steroid PCPB. Pancreas 5:725

    Google Scholar 

  8. Bengtsson M, Lofstrom JB (1990) Nerve block in pancreatic pain. Acta Chir Scand 156:285–291

    PubMed  CAS  Google Scholar 

  9. Ihse I, Permerth J (1990) Enzyme therapy and pancreatic pain. Acta Chir Scand 156:281–283

    PubMed  CAS  Google Scholar 

  10. Huibregtse K, Schneider B, Vrij AA, Tytgat (1988) Endoscopic pancreatic drainage in chronic pancreatitis. Gastrointest Endosc 34:9–15

    Article  PubMed  CAS  Google Scholar 

  11. McCarthy J, Geenen JE, Hogan WJ (1988) Preliminary experience with endoscopic stent placement in benign pancreatic diseases. Gastrointest Endosc 34:16–18

    Article  PubMed  CAS  Google Scholar 

  12. Kozarek RE (1989) Pancreatic stents can induce ductal changes consistent with chronic pancreatitis. Gastrointest Endosc 35.A170

    Google Scholar 

  13. Derfus GA, Geenen JE, Hogan WJ (1989) Alterations in pancreatic duct morphology associated with endoscopic stent placement. Pancreas 4:613

    Google Scholar 

  14. Regan PT, Malagelada J-R, DiMagno EP, Glanzman SL, and Go VLW (1977) Comparative effects of antacids, Cimetidine, and enteric coating on the therapeutic response to oral enzymes in severe pancreatic insufficiency. N Engl J Med 297:854–858

    Article  PubMed  CAS  Google Scholar 

  15. Regan PT, Malagelada J-R, DiMagno EP, Go VLW (1979) Reduced intraluminal bile acid concentrations and fat maldigestion in pancreatic insufficiency: correction by treatment. Gastroenterology 77:285–289

    PubMed  CAS  Google Scholar 

  16. Thiruvengadam R, DiMagno EP (1988) Inactivation of human lipase by proteases. Am J Physiol 255:G476-G481

    PubMed  CAS  Google Scholar 

  17. Mundlos S, Kühnelt P, Adler G (1990) Monitoring enzyme replacement treatment in exocrine pancreatic insufficiency using the cholesteryl octanoate breath test. Gut 31:1324–1328

    Article  PubMed  CAS  Google Scholar 

  18. Andersen JR, Bendtsen F, Ovesen L, Pedersen NT, Rune SJ, Tage-Jensen U (1990) Pancreatic insufficiency. Duodenal and jejunal pH, bile acid activity, and micellar lipid solubilization. Int J Pancreatol 6:263–270

    PubMed  CAS  Google Scholar 

  19. Kelly DG, Sternby B, DiMagno EP (1991) How to protect human pancreatic enzyme activities in frozen duodenal juice. Gastroenterology 100:189–195

    PubMed  CAS  Google Scholar 

  20. Graham DY (1982) Pancreatic enzyme replacement: the effect of antacids or Cimetidine. Dig Dis Sci 27:485–490

    Article  PubMed  CAS  Google Scholar 

  21. Schneider MU, Knoll-Ruzicka ML, Domschke S, Heptner G, Domschke W (1985) Pancreatic enzyme replacement therapy: comparative effects of conventional and enteric-coated microspheric pancreatin and acid-stable fungal enzyme preparations on steatorrhoea in chronic pancreatitis. Hepatogastroenterology 32:97–102

    PubMed  CAS  Google Scholar 

  22. Robinson PJ, Sly PD (1990) High-dose pancreatic enzymes in cystic fibrosis. Arch Dis Child 65:311–312

    Article  PubMed  CAS  Google Scholar 

  23. Williams J, MacDonald A, Weller PH, Fields J, Pandov H (1990) Two enteric coated microspheres in cystic fibrosis. Arch Dis Child 65:594–597

    Article  PubMed  CAS  Google Scholar 

  24. Jorgensen BB, Thorsgaard Pedersen N, Worning H (1991) Monitoring the effect of substitution therapy in patients with exocrine pancreatic insufficiency. Scand J Gastroenterol 26:321–326

    Article  PubMed  CAS  Google Scholar 

  25. Hendeles L, Dorf A, Stecenko A, Weinberger M (1990) Treatment failure after substitution of generic pancrelipase capsules. JAMA 263:2459–2461

    Article  PubMed  CAS  Google Scholar 

  26. Gullo L, Parenti M, Monti L, Pezzilli R, Barbara L (1990) Diabetic retinopathy in chronic pancreatitis. Gastroenterology 98:1577–1581

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

DiMagno, E.P. (1993). Conservative Management of Chronic Pancreatitis. In: Beger, H.G., Büchler, M., Malfertheiner, P. (eds) Standards in Pancreatic Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77437-9_36

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-77437-9_36

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77439-3

  • Online ISBN: 978-3-642-77437-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics