Bacterial Infection and the Role of Fine Needle Aspiration

  • W. Uhl
  • M. Büchler
  • B. Rau
  • H. G. Beger


There is general agreement among clinicians and pancreatologists that pancreatic infection is the most important causal factor of lethal outcome in human acute pancreatitis today [1–3]. Bacterial contamination of pancreatic necrosis has been demonstrated in 40%–70% of patients suffering from necrotizing pancreatitis [4–8], and it has been shown that the frequency of positive cultures increases directly with the duration and extent of necrosis. The necroses in 24% of patients with necrotizing pancreatitis operated on during the first week after hospitalization showed bacterial contamination. This percentage increased to 36% in the second week and to 72% in the third week; thereafter a decrease was found to 32% [9]. Bacterial contamination of pancreatic necrosis occurs early and frequently, as verified by Bassi in a similar study and by Gerzof with the aid of computed tomography (CT)-guided fine needle aspiration and Gram staining [5, 6].


Acute Pancreatitis Fine Needle Aspiration Acute pancreatitIs Severe Acute Pancreatitis Pancreatic Necrosis 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • W. Uhl
  • M. Büchler
  • B. Rau
  • H. G. Beger
    • 1
  1. 1.Department of General SurgeryUniversity of UlmUlmGermany

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