Bacterial Infection and the Role of Fine Needle Aspiration
There is general agreement among clinicians and pancreatologists that pancreatic infection is the most important causal factor of lethal outcome in human acute pancreatitis today [1–3]. Bacterial contamination of pancreatic necrosis has been demonstrated in 40%–70% of patients suffering from necrotizing pancreatitis [4–8], and it has been shown that the frequency of positive cultures increases directly with the duration and extent of necrosis. The necroses in 24% of patients with necrotizing pancreatitis operated on during the first week after hospitalization showed bacterial contamination. This percentage increased to 36% in the second week and to 72% in the third week; thereafter a decrease was found to 32% . Bacterial contamination of pancreatic necrosis occurs early and frequently, as verified by Bassi in a similar study and by Gerzof with the aid of computed tomography (CT)-guided fine needle aspiration and Gram staining [5, 6].
KeywordsCatheter Creatinine Pancreatitis Pseudomonas Ampicillin
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