Abstract
Three groups of 40 patients each entered this prospective randomized trial. Patients of group A received 2 ml/kg body weight CMV-Polyglobulin, patients of group B 15 g Intraglobin and patients of group C, serving as controls, received no specific anti-CMV prophylaxis. All patients were given the same sequential immunosuppressive therapy. Patient survival and graft function did not show any significant differences at 2 years follow up. The incidence of fever, CMV infections, dialysis and steroid bolus therapy were lower in group A, but without statistical significance. Patients receiving a graft from a CMV-AK-positive donor were at high risk of developing an infection or reactivation of CMV. A study examining this subgroup seems appropriate.
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© 1992 Springer-Verlag Berlin Heidelberg
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Stippel, D., Wienand, P., Weißenberg, N., Baldamus, C., Kruppenbacher, U. (1992). CMV prophylaxis after renal transplantation with immunoglobulin or CMV-hyperimmunoglobulin — a prospective clinical trial. In: Kootstra, G., Opelz, G., Buurman, W.A., van Hooff, J.P., MacMaster, P., Wallwork, J. (eds) Transplant International Official Journal of the European Society for Organ Transplantation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77423-2_46
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DOI: https://doi.org/10.1007/978-3-642-77423-2_46
Publisher Name: Springer, Berlin, Heidelberg
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