A logical basis for age matching in organ transplantation: studies of recipient renal function in relation to donor age

  • P. K. Donnelly
  • G. Mobb
  • A. R. Simpson
  • P. S. Veitch
  • P. R. F. Bell
Conference paper

Abstract

The ever rising demand for renal transplantation has led to an increased use of older (> 50 years) organ donors [9]. Previous studies have shown that donor-to-recipient age difference is an independent risk factor for allograft survival [3]. A recent multicentre study of 6397 first cadaver renal transplants showed that, where donors are more than 5 years older than the recipient, there is significantly impaired graft survival [11]. The mechanism of this effect is unclear, but it has been suggested that age-related donor factors may influence subsequent graft function.

Key words

Renal transplantation Donor age Kidney function 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • P. K. Donnelly
    • 1
  • G. Mobb
    • 1
  • A. R. Simpson
    • 1
  • P. S. Veitch
    • 1
  • P. R. F. Bell
    • 1
  1. 1.Department of SurgeryLeicester UniversityUK

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