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Antibiotics Secretion into Pancreatic Fluid

  • N. Martini
  • S. Vesentini
  • C. Bassi
  • M. Falconi
  • R. Girelli
  • A. Messori
  • P. Pederzoli

Abstract

The development of infective complications in patients with acute pancreatitits and pancreatic fistula is an unfavorable prognistic factor [1–4]. These complications are frequent (from 1 % [4] to 29 % [ 1]) and imply a high rate of morbidity and mortality [2–4]. The therapeutic management of such infections has been the subject of previous reviews [5–7]; however, the problem of the selection of appropriate antimicrobial agents in acute pancreatitis and its complications has not recently been addressed specifically, although new antibiotics have been introduced which are potentially useful for this indication. The present article summarizes the pharmacokinetic data on the penetration of antibiotics in pancreatic tissue and reviews the current information on the bacterial strains involved in this disease.

Keywords

Acute Pancreatitis Acute Pancreatits Pancreatic Fistula Pancreatic Tissue Pancreatic Juice 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • N. Martini
  • S. Vesentini
  • C. Bassi
  • M. Falconi
  • R. Girelli
  • A. Messori
  • P. Pederzoli

There are no affiliations available

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