In Vitro Production and Secretion of Interleukin-1 by Human Monocytes After Surgical Trauma

  • M. L. Vuotto
  • E. Bresciano
  • D. Mancino
  • M. T. Ielpo
  • M. R. Mosti
  • G. De Martino
  • A. Barbarisi

Abstract

Interleukin-1 (IL-1) is a cytokine produced by different cells, the principal ones being mononuclear phagocytes. This cytokine functions as a key mediator in the organism’s response to various stimuli principally modulating target cell growth and differentiation. IL-1 is part of a complex of soluble mediators forming the biological and molecular cornerstone of the lymphomonokine network that, in turn, links the immune system to other systems [2].

Keywords

Prostaglandin Fentanyl Indomethacin Thymidine Cephalosporin 

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Copyright information

© Springer-Verlag, Berlin Heidelberg 1993

Authors and Affiliations

  • M. L. Vuotto
    • 1
  • E. Bresciano
    • 1
  • D. Mancino
    • 1
  • M. T. Ielpo
    • 1
  • M. R. Mosti
    • 1
  • G. De Martino
    • 2
  • A. Barbarisi
    • 2
  1. 1.Institute of General Pathology and Oncology, First School of Medicine and SurgeryUniversity of NaplesNaplesItaly
  2. 2.Institute of Surgery and Surgical Therapy, First School of Medicine and SurgeryUniversity of NaplesNaplesItaly

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