Decrease in Leukotriene Synthesis from Leukocytes Isolated in Septic Patients
Many experimental and clinical investigations support the hypothesis that the leukotrienes are likely contributors to the nonhydrostatic edema associated with organ damage in sepsis [1–8]. In this study the capacity of leukocytes to synthesize leukotrienes was measured. The production of leukotriene C4 (LTC4) from leukocytes isolated in septic patients was compared to the values obtained in healthy volunteers.
KeywordsDepression Pneumonia Prostaglandin Glucocorticoid Gall
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