Diagnostic Role of New Mediators and Markers of Inflammation in Multiple Injured Patients
The major cause of late death after severe blunt trauma is (multiple) organ failure (OF), which is a direct consequence of mediators released during primary tissue damage and circulatory shock. To further elucidate the role of inflammatory mediators in the development of OF we performed a prospective study in severely injured patients. In a second step we examined the early prognostic value of objective biochemical markers for death and the development of OF compared to the Injury Severity Score (ISS).
KeywordsOrgan Failure Injury Severity Score Disseminate Intravascular Coagulation Adult Respiratory Distress Syndrome Lethal Outcome
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