Protein Synthesis Inhibitors and Bacterial Susceptibility to Phagocytosis

  • C. G. Gemmell


It is well recognised that antibiotics can be either bactericidal or bacteriostatic and on this basis their therapeutic efficacy can be measured. In particular those drugs in the latter category may depend upon the underlying activity of the host’s reticulo-endothelial system (RES) in order to demonstrate their full efficacy. Antibiotics whose mode of action is based upon bacterial ribosomal protein biosynthesis are usually bacteriostatic, and this article will concentrate on their bioactivity in concert with phagocytic cells.


Protein Synthesis Inhibitor Fusidic Acid Polymorphonuclear Leucocyte Subinhibitory Concentration Bacterial Susceptibility 
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Copyright information

© Springer-Verlag, Berlin Heidelberg 1993

Authors and Affiliations

  • C. G. Gemmell
    • 1
  1. 1.Department of BacteriologyRoyal InfirmaryGlasgowUK

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