Selective Decontamination of the Digestive Tract (SDD): Review of Available Clinical Studies
Selective decontamination of the digestive tract (SDD) is based on two observations: first, most infections in intensive care are endogenous, i.e. caused by potential pathogens carried in the throat and gastrointestinal tract; secondly, the indigenous, mostly anaerobic flora has a very low intrinsic pathogenicity and helps to prevent colonization by more pathogenic exogenous microorganisms. SDD aims to selectively eliminate pathogens from the oropharynx and gastrointestinal tract by high doses of topical nonabsorbable antibiotics, which affect the indigenous flora as little as possible.
KeywordsBacillus Pseudomonas Ampicillin Vancomycin Gentamicin
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