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Gut-Derived Infectious-Toxic Shock Syndrome: Therapeutic Chances with Polyspecific Immunoglobulins

  • H. Cottier
  • A. Hässig
  • R. Kraft

Abstract

Septic shock is probably the most feared complication of major surgery, especially of interventions in the abdominal cavity [1]. Frequently, but by no means always, bacteremia accompanies this condition, and gram-negative microbes predominate as causative agents. This points to the intestine as the main source of infection, i.e. it involves—at least in many cases—a gut-derived infectious-toxic shock (GITS). Despite considerable progress in antibiotic therapy and supportive care, the fatality rate has remained high [2]. There is thus a need for novel strategies.

Keywords

Septic Shock Adult Respiratory Distress Syndrome Passive Immunization Treated Poly Rough Mutant 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag, Berlin Heidelberg 1993

Authors and Affiliations

  • H. Cottier
    • 1
  • A. Hässig
    • 2
  • R. Kraft
    • 2
  1. 1.Zeutrallaboratorium Blutspendedienst SRKBern 2Switzerland
  2. 2.Central Laboratory Swiss Red Cross Blood Transfusion Service, and Institute of PathologyUniversity of BernBernSwitzerland

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