Use of Monophosphoryl Lipid A as a Prophylactic for Sepsis and Shock

  • J. A. Rudbach
  • J. T. Ulrich
  • K. B. Von Eschen
  • J. D. Beatty


Of patients who ultimately develop gram-negative sepsis and shock, many can be identified for inclusion into high-risk groups [1–3]. These groups include patients subjected to certain types of surgeries, some with traumatic injuries, and those with depressed immune systems. Appropriate immunomodulation of patients in these groups should be able to prevent or ameliorate septic shock.


Septic Shock Continuous Ambulatory Peritoneal Dialysis Endotoxin Tolerance Monophosphoryl Lipid Serum Neopterin 
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Copyright information

© Springer-Verlag, Berlin Heidelberg 1993

Authors and Affiliations

  • J. A. Rudbach
    • 1
  • J. T. Ulrich
    • 1
  • K. B. Von Eschen
    • 1
  • J. D. Beatty
    • 2
  1. 1.Ribi ImmunoChem Research, Inc.HamiltonUSA
  2. 2.Division of SurgeryCity of Hope National Medical CenterDuarteUSA

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