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In-vitro- und in-vivo Untersuchungen zur Perichondriumtransplantation beim Schaf zur Behebung von tiefreichenden Gelenkknorpeldefekten

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Fibrinklebung in der Allgemein- und Unfallchirurgie, Orthopädie, Kinder- und Thoraxchirurgie

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Zusammenfassung

Die Behandlung umschriebener Knorpeldefekte am hyalinen Gelenkknorpel stellt ein therapeutisches Problem besonders an den gewichtsbelasteten Gelenken und besonders beim Sportler dar (10, 21, 48, 52). Wenige Behandlungsmethoden werden bisher klinisch umfangreich mit hinreichendem Erfolg angewendet (47, 48). Unter den bisher experimentell untersuchten Transplantationsmethoden stellt die autologe Perichondriumtransplantation aufgrund ihrer Proliferationsfähigkeit ein interessantes Verfahren dar (2, 12, 13, 15, 32, 36, 42, 43). Bisher wurde diese Methode im Tiermodell nur am Kaninchen und Hund untersucht (13, 14, 23), wenige Berichte liegen über die Anwendung beim Menschen vor. Diese zeigten an nicht gewichtsbelasteten Gelenken wie Finger- und Handgelenken gute Ergebnisse auf (11, 25, 29, 32, 37, 40, 45). Neuere Berichte von Homminga (24), zeigten gute Ergebnisse auch bei der klinischen Anwendung an Kniegelenken.

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Authors
  1. J. Bruns
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  1. Chirurgische Klinik, Flurstraße 17, W-8500, Nürnberg, Bundesrepublik Deutschland

    Ch. Gebhardt

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© 1992 Springer-Verlag Berlin Heidelberg

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Bruns, J. (1992). In-vitro- und in-vivo Untersuchungen zur Perichondriumtransplantation beim Schaf zur Behebung von tiefreichenden Gelenkknorpeldefekten. In: Gebhardt, C. (eds) Fibrinklebung in der Allgemein- und Unfallchirurgie, Orthopädie, Kinder- und Thoraxchirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77386-0_27

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  • DOI: https://doi.org/10.1007/978-3-642-77386-0_27

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-55302-1

  • Online ISBN: 978-3-642-77386-0

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